LYL1: Difference between revisions

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Identifiers
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External IDs	GeneCards: [1]
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Latest revision as of 11:23, 2 January 2018

Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene.^[1]^[2]

Interactions

LYL1 has been shown to interact with TCF3^[3] and NFKB1.^[4]

References

↑ Mellentin JD, Smith SD, Cleary ML (July 1989). "lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif". Cell. 58 (1): 77–83. doi:10.1016/0092-8674(89)90404-2. PMID 2752424.
↑ "Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1".
↑ Miyamoto A, Cui X, Naumovski L, Cleary ML (May 1996). "Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells". Molecular and Cellular Biology. 16 (5): 2394–401. doi:10.1128/mcb.16.5.2394. PMC 231228. PMID 8628307.
↑ Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D (January 1999). "Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105". Oncogene. 18 (4): 995–1005. doi:10.1038/sj.onc.1202374. PMID 10023675.

Xia Y, Brown L, Yang CY, Tsan JT, Siciliano MJ, Espinosa R, Le Beau MM, Baer RJ (December 1991). "TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia". Proceedings of the National Academy of Sciences of the United States of America. 88 (24): 11416–20. doi:10.1073/pnas.88.24.11416. PMC 53146. PMID 1763056.
Kuo SS, Mellentin JD, Copeland NG, Gilbert DJ, Jenkins NA, Cleary ML (June 1991). "Structure, chromosome mapping, and expression of the mouse Lyl-1 gene". Oncogene. 6 (6): 961–8. PMID 2067848.
Saltman DL, Mellentin JD, Smith SD, Cleary ML (November 1990). "Mapping of translocation breakpoints on the short arm of chromosome 19 in acute leukemias by in situ hybridization". Genes, Chromosomes & Cancer. 2 (4): 259–65. doi:10.1002/gcc.2870020402. PMID 2268576.
Wadman I, Li J, Bash RO, Forster A, Osada H, Rabbitts TH, Baer R (October 1994). "Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia". The EMBO Journal. 13 (20): 4831–9. PMC 395422. PMID 7957052.
Trask B, Fertitta A, Christensen M, Youngblom J, Bergmann A, Copeland A, de Jong P, Mohrenweiser H, Olsen A, Carrano A (January 1993). "Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers". Genomics. 15 (1): 133–45. doi:10.1006/geno.1993.1021. PMID 8432525.
Miyamoto A, Cui X, Naumovski L, Cleary ML (May 1996). "Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells". Molecular and Cellular Biology. 16 (5): 2394–401. doi:10.1128/mcb.16.5.2394. PMC 231228. PMID 8628307.
Mahajan MA, Park ST, Sun XH (June 1996). "Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins". Oncogene. 12 (11): 2343–50. PMID 8649774.
Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D (January 1999). "Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105". Oncogene. 18 (4): 995–1005. doi:10.1038/sj.onc.1202374. PMID 10023675.
Meng YS, Khoury H, Dick JE, Minden MD (November 2005). "Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia". Leukemia. 19 (11): 1941–7. doi:10.1038/sj.leu.2403836. PMID 16094422.

External links

LYL1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[pmid2752424-1] Mellentin JD, Smith SD, Cleary ML (July 1989). "lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif". Cell. 58 (1): 77–83. doi:10.1016/0092-8674(89)90404-2. PMID 2752424.

[entrez-2] "Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1".

[pmid8628307-3] Miyamoto A, Cui X, Naumovski L, Cleary ML (May 1996). "Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells". Molecular and Cellular Biology. 16 (5): 2394–401. doi:10.1128/mcb.16.5.2394. PMC 231228. PMID 8628307.

[pmid10023675-4] Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D (January 1999). "Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105". Oncogene. 18 (4): 995–1005. doi:10.1038/sj.onc.1202374. PMID 10023675.

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@@ Line 1: / Line 1: @@
 {{Infobox_gene}}
-'''Protein lyl-1''' is a [[protein]] that in humans is encoded by the ''LYL1'' [[gene]].<ref name="pmid2752424">{{cite journal |vauthors=Mellentin JD, Smith SD, Cleary ML | title = lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif | journal = Cell | volume = 58 | issue = 1 | pages = 77–83 |date=Aug 1989 | pmid = 2752424 | pmc =  | doi =10.1016/0092-8674(89)90404-2  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4066| accessdate = }}</ref>
+'''Protein lyl-1''' is a [[protein]] that in humans is encoded by the ''LYL1'' [[gene]].<ref name="pmid2752424">{{cite journal | vauthors = Mellentin JD, Smith SD, Cleary ML | title = lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif | journal = Cell | volume = 58 | issue = 1 | pages = 77–83 | date = July 1989 | pmid = 2752424 | pmc =  | doi = 10.1016/0092-8674(89)90404-2 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4066| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==Interactions==
+LYL1 has been shown to [[Protein-protein interaction|interact]] with [[TCF3]]<ref name=pmid8628307>{{cite journal | vauthors = Miyamoto A, Cui X, Naumovski L, Cleary ML | title = Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells | journal = Molecular and Cellular Biology | volume = 16 | issue = 5 | pages = 2394–401 | date = May 1996 | pmid = 8628307 | pmc = 231228 | doi = 10.1128/mcb.16.5.2394 }}</ref> and [[NFKB1]].<ref name=pmid10023675>{{cite journal | vauthors = Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D | title = Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105 | journal = Oncogene | volume = 18 | issue = 4 | pages = 995–1005 | date = January 1999 | pmid = 10023675 | doi = 10.1038/sj.onc.1202374 }}</ref>
-LYL1 has been shown to [[Protein-protein interaction|interact]] with [[TCF3]]<ref name=pmid8628307>{{cite journal |last=Miyamoto |first=A |authorlink= |author2=Cui X |author3=Naumovski L |author4=Cleary M L  |date=May 1996 |title=Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells |journal=Mol. Cell. Biol. |volume=16 |issue=5 |pages=2394–401 |publisher= |location = UNITED STATES| issn = 0270-7306| pmid = 8628307 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=231228 | doi=10.1128/mcb.16.5.2394}}</ref> and [[NFKB1]].<ref name=pmid10023675>{{cite journal |last=Ferrier |first=R |authorlink= |author2=Nougarede R |author3=Doucet S |author4=Kahn-Perles B |author5=Imbert J |author6=Mathieu-Mahul D  |date=Jan 1999 |title=Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105 |journal=Oncogene |volume=18 |issue=4 |pages=995–1005 |publisher= |location = ENGLAND| issn = 0950-9232| pmid = 10023675 |doi = 10.1038/sj.onc.1202374 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref>
-==References==
+== References ==
 {{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Xia Y, Brown L, Yang CY, Tsan JT, Siciliano MJ, Espinosa R, Le Beau MM, Baer RJ | title = TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 88 | issue = 24 | pages = 11416–20 | date = December 1991 | pmid = 1763056 | pmc = 53146 | doi = 10.1073/pnas.88.24.11416 }}
-| citations =
+* {{cite journal | vauthors = Kuo SS, Mellentin JD, Copeland NG, Gilbert DJ, Jenkins NA, Cleary ML | title = Structure, chromosome mapping, and expression of the mouse Lyl-1 gene | journal = Oncogene | volume = 6 | issue = 6 | pages = 961–8 | date = June 1991 | pmid = 2067848 | doi =  }}
-*{{cite journal   |vauthors=Xia Y, Brown L, Yang CY, etal |title=TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 24 |pages= 11416–20 |year= 1992 |pmid= 1763056 |doi=10.1073/pnas.88.24.11416  | pmc=53146  }}
+* {{cite journal | vauthors = Saltman DL, Mellentin JD, Smith SD, Cleary ML | title = Mapping of translocation breakpoints on the short arm of chromosome 19 in acute leukemias by in situ hybridization | journal = Genes, Chromosomes & Cancer | volume = 2 | issue = 4 | pages = 259–65 | date = November 1990 | pmid = 2268576 | doi = 10.1002/gcc.2870020402 }}
-*{{cite journal   |vauthors=Kuo SS, Mellentin JD, Copeland NG, etal |title=Structure, chromosome mapping, and expression of the mouse Lyl-1 gene. |journal=Oncogene |volume=6 |issue= 6 |pages= 961–8 |year= 1991 |pmid= 2067848 |doi=  }}
+* {{cite journal | vauthors = Wadman I, Li J, Bash RO, Forster A, Osada H, Rabbitts TH, Baer R | title = Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia | journal = The EMBO Journal | volume = 13 | issue = 20 | pages = 4831–9 | date = October 1994 | pmid = 7957052 | pmc = 395422 | doi =  }}
-*{{cite journal  |vauthors=Saltman DL, Mellentin JD, Smith SD, Cleary ML |title=Mapping of translocation breakpoints on the short arm of chromosome 19 in acute leukemias by in situ hybridization. |journal=Genes Chromosomes Cancer |volume=2 |issue= 4 |pages= 259–65 |year= 1991 |pmid= 2268576 |doi=10.1002/gcc.2870020402  }}
+* {{cite journal | vauthors = Trask B, Fertitta A, Christensen M, Youngblom J, Bergmann A, Copeland A, de Jong P, Mohrenweiser H, Olsen A, Carrano A | title = Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers | journal = Genomics | volume = 15 | issue = 1 | pages = 133–45 | date = January 1993 | pmid = 8432525 | doi = 10.1006/geno.1993.1021 }}
-*{{cite journal   |vauthors=Wadman I, Li J, Bash RO, etal |title=Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. |journal=EMBO J. |volume=13 |issue= 20 |pages= 4831–9 |year= 1994 |pmid= 7957052 |doi=  | pmc=395422  }}
+* {{cite journal | vauthors = Miyamoto A, Cui X, Naumovski L, Cleary ML | title = Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells | journal = Molecular and Cellular Biology | volume = 16 | issue = 5 | pages = 2394–401 | date = May 1996 | pmid = 8628307 | pmc = 231228 | doi = 10.1128/mcb.16.5.2394 }}
-*{{cite journal   |vauthors=Trask B, Fertitta A, Christensen M, etal |title=Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers. |journal=Genomics |volume=15 |issue= 1 |pages= 133–45 |year= 1993 |pmid= 8432525 |doi=10.1006/geno.1993.1021  }}
+* {{cite journal | vauthors = Mahajan MA, Park ST, Sun XH | title = Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins | journal = Oncogene | volume = 12 | issue = 11 | pages = 2343–50 | date = June 1996 | pmid = 8649774 | doi =  }}
-*{{cite journal  |vauthors=Miyamoto A, Cui X, Naumovski L, Cleary ML |title=Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells. |journal=Mol. Cell. Biol. |volume=16 |issue= 5 |pages= 2394–401 |year= 1996 |pmid= 8628307 |doi=  10.1128/mcb.16.5.2394| pmc=231228  }}
+* {{cite journal | vauthors = Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J, Mathieu-Mahul D | title = Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105 | journal = Oncogene | volume = 18 | issue = 4 | pages = 995–1005 | date = January 1999 | pmid = 10023675 | doi = 10.1038/sj.onc.1202374 }}
-*{{cite journal  |vauthors=Mahajan MA, Park ST, Sun XH |title=Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins. |journal=Oncogene |volume=12 |issue= 11 |pages= 2343–50 |year= 1996 |pmid= 8649774 |doi=  }}
+* {{cite journal | vauthors = Meng YS, Khoury H, Dick JE, Minden MD | title = Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia | journal = Leukemia | volume = 19 | issue = 11 | pages = 1941–7 | date = November 2005 | pmid = 16094422 | doi = 10.1038/sj.leu.2403836 }}
-*{{cite journal   |vauthors=Ferrier R, Nougarede R, Doucet S, etal |title=Physical interaction of the bHLH LYL1 protein and NF-kappaB1 p105. |journal=Oncogene |volume=18 |issue= 4 |pages= 995–1005 |year= 1999 |pmid= 10023675 |doi= 10.1038/sj.onc.1202374 }}
-*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal   |vauthors=Grimwood J, Gordon LA, Olsen A, etal |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
-*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  |vauthors=Meng YS, Khoury H, Dick JE, Minden MD |title=Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia. |journal=Leukemia |volume=19 |issue= 11 |pages= 1941–7 |year= 2005 |pmid= 16094422 |doi= 10.1038/sj.leu.2403836 }}
-}}
 {{refend}}
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 {{Transcription factors|g1}}
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-{{PBB_Controls
-| update_page = yes
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 [[Category:Transcription factors]]
 {{gene-19-stub}}

LYL1: Difference between revisions

Latest revision as of 11:23, 2 January 2018

Contents

Interactions

References

Further reading

External links

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