HMGA
| high mobility group AT-hook 1
| |
| Identifiers | |
| Symbol | HMGA1 |
| Alt. Symbols | HMGIY |
| Entrez | 3159 |
| HUGO | 5010 |
| OMIM | 600701 |
| RefSeq | NM_145901 |
| UniProt | P17096 |
| Other data | |
| Locus | Chr. 6 p21 |
| high mobility group AT-hook 2
| |
| Identifiers | |
| Symbol | HMGA2 |
| Alt. Symbols | HMGIC |
| Entrez | 8091 |
| HUGO | 5009 |
| OMIM | 600698 |
| RefSeq | NM_003484 |
| UniProt | P52926 |
| Other data | |
| Locus | Chr. 12 q15 |
HMGA is a family of high mobility group proteins characterized by an AT-hook. They code for a "small, nonhistone, chromatin-associated protein that has no intrinsic transcriptional activity but can modulate transcription by altering the chromatin architecture" (Mayr, SCIENCE)
A recent study has shown variations in HMGA2 to have a moderate association with adult height.[1]
References
- ↑ BBC NEWS. Retrieved on 2007-09-03.
Mayr, Christine, et. al. Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation, SCIENCE VOL 315, 16 Mar 2007
External links
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