POU3F1

POU domain, class 3, transcription factor 1
Identifiers
Symbol(s)	POU3F1; OCT6; OTF6; SCIP
External IDs	OMIM: 602479 MGI: 101896 Homologene: 20590
Gene ontology Molecular Function: • transcription factor activity • sequence-specific DNA binding Cellular Component: • nucleus Biological Process: • regulation of transcription, DNA-dependent • axon ensheathment
RNA expression pattern
250px 250px More reference expression data
Orthologs
	Human	Mouse
Entrez	5453	18991
Ensembl	ENSG00000185668	na
Uniprot	Q03052	na
Refseq	NM_002699 (mRNA) NP_002690 (protein)	XM_980403 (mRNA) XP_985497 (protein)
Location	Chr 1: 38.28 - 38.29 Mb	na
Pubmed search	[1]	[2]

POU domain, class 3, transcription factor 1, also known as POU3F1, is a human gene.

See also

• Octamer transcription factor

Further reading

• Monuki ES, Kuhn R, Weinmaster G, et al. (1990). "Expression and activity of the POU transcription factor SCIP.". Science 249 (4974): 1300-3. PMID 1975954.
• Suzuki N, Rohdewohld H, Neuman T, et al. (1990). "Oct-6: a POU transcription factor expressed in embryonal stem cells and in the developing brain.". EMBO J. 9 (11): 3723-32. PMID 1976514.
• Zwilling S, König H, Wirth T (1995). "High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.". EMBO J. 14 (6): 1198-208. PMID 7720710.
• Leger H, Sock E, Renner K, et al. (1995). "Functional interaction between the POU domain protein Tst-1/Oct-6 and the high-mobility-group protein HMG-I/Y.". Mol. Cell. Biol. 15 (7): 3738-47. PMID 7791781.
• Faus I, Hsu HJ, Fuchs E (1994). "Oct-6: a regulator of keratinocyte gene expression in stratified squamous epithelia.". Mol. Cell. Biol. 14 (5): 3263-75. PMID 7909356.
• Tobler A, Schreiber E, Fontana A (1993). "The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart.". Nucleic Acids Res. 21 (4): 1043. PMID 8451175.
• Abdel-Rahman B, Fiddler M, Rappolee D, Pergament E (1996). "Expression of transcription regulating genes in human preimplantation embryos.". Hum. Reprod. 10 (10): 2787-92. PMID 8567814.
• Jaegle M, Mandemakers W, Broos L, et al. (1996). "The POU factor Oct-6 and Schwann cell differentiation.". Science 273 (5274): 507-10. PMID 8662541.
• Sock E, Enderich J, Rosenfeld MG, Wegner M (1996). "Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6.". J. Biol. Chem. 271 (29): 17512-8. PMID 8663425.
• Malik KF, Jaffe H, Brady J, Young WS (1997). "The class III POU factor Brn-4 interacts with other class III POU factors and the heterogeneous nuclear ribonucleoprotein U.". Brain Res. Mol. Brain Res. 45 (1): 99-107. PMID 9105675.
• Sumiyama K, Washio-Watanabe K, Ono T, et al. (1998). "Human class III POU genes, POU3F1 and POU3F3, map to chromosomes 1p34.1 and 3p14.2.". Mamm. Genome 9 (2): 180-1. PMID 9457692.
• Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS (1998). "Promyelinating Schwann cells express Tst-1/SCIP/Oct-6.". J. Neurosci. 18 (19): 7891-902. PMID 9742157.
• Kawasaki T, Oka N, Tachibana H, et al. (2003). "Oct6, a transcription factor controlling myelination, is a marker for active nerve regeneration in peripheral neuropathies.". Acta Neuropathol. 105 (3): 203-8. doi:10.1007/s00401-002-0630-9. PMID 12557005.
• Beck IM, Müller M, Mentlein R, et al. (2007). "Matrix metalloproteinase-19 expression in keratinocytes is repressed by transcription factors Tst-1 and Skn-1a: implications for keratinocyte differentiation.". J. Invest. Dermatol. 127 (5): 1107-14. doi:10.1038/sj.jid.5700674. PMID 17195013.
• Ryu EJ, Wang JY, Le N, et al. (2007). "Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss.". J. Neurosci. 27 (43): 11552-9. doi:10.1523/JNEUROSCI.5497-06.2007. PMID 17959798.

External links

• MeSH POU3F1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.