KLF11
| Kruppel-like factor 11 | |||||||||||
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| Identifiers | |||||||||||
| Symbols | KLF11 ; FKLF; FKLF1; MODY7; TIEG2; Tieg3 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 2668 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE KLF11 218486 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Kruppel-like factor 11, also known as KLF11, is a human gene.[1]
See also
References
Further reading
- Cook T, Gebelein B, Mesa K; et al. (1998). "Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth". J. Biol. Chem. 273 (40): 25929–36. PMID 9748269.
- Asano H, Li XS, Stamatoyannopoulos G (1999). "FKLF, a novel Krüppel-like factor that activates human embryonic and fetal beta-like globin genes". Mol. Cell. Biol. 19 (5): 3571–9. PMID 10207080.
- Scohy S, Gabant P, Van Reeth T; et al. (2001). "Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family". Genomics. 70 (1): 93–101. doi:10.1006/geno.2000.6362. PMID 11087666.
- Zhang JS, Moncrieffe MC, Kaczynski J; et al. (2001). "A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A". Mol. Cell. Biol. 21 (15): 5041–9. doi:10.1128/MCB.21.15.5041-5049.2001. PMID 11438660.
- Jia L, Young MF, Powell J; et al. (2002). "Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis". Genomics. 79 (1): 7–17. doi:10.1006/geno.2001.6683. PMID 11827452.
- Ellenrieder V, Zhang JS, Kaczynski J, Urrutia R (2002). "Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor". EMBO J. 21 (10): 2451–60. doi:10.1093/emboj/21.10.2451. PMID 12006497.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Ou XM, Chen K, Shih JC (2004). "Dual functions of transcription factors, transforming growth factor-beta-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B gene". J. Biol. Chem. 279 (20): 21021–8. doi:10.1074/jbc.M312638200. PMID 15024015.
- Ellenrieder V, Buck A, Harth A; et al. (2004). "KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells". Gastroenterology. 127 (2): 607–20. PMID 15300592.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Cao S, Fernandez-Zapico ME, Jin D; et al. (2005). "KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling". J. Biol. Chem. 280 (3): 1901–10. doi:10.1074/jbc.M407941200. PMID 15531587.
- Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V; et al. (2005). "Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function". Proc. Natl. Acad. Sci. U.S.A. 102 (13): 4807–12. doi:10.1073/pnas.0409177102. PMID 15774581.
- Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- Buck A, Buchholz M, Wagner M; et al. (2007). "The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer". Mol. Cancer Res. 4 (11): 861–72. doi:10.1158/1541-7786.MCR-06-0081. PMID 17114344.
- Florez JC, Saxena R, Winckler W; et al. (2007). "The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people". Diabetes. 55 (12): 3620–4. doi:10.2337/db06-0867. PMID 17130512.
- Spittau B, Wang Z, Boinska D, Krieglstein K (2007). "Functional domains of the TGF-beta-inducible transcription factor Tieg3 and detection of two putative nuclear localization signals within the zinc finger DNA-binding domain". J. Cell. Biochem. 101 (3): 712–22. doi:10.1002/jcb.21228. PMID 17252542.
- Niu X, Perakakis N, Laubner K; et al. (2007). "Human Krüppel-like factor 11 inhibits human proinsulin promoter activity in pancreatic beta cells". Diabetologia. 50 (7): 1433–41. doi:10.1007/s00125-007-0667-3. PMID 17479246.
External links
- KLF11+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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