IKZF3: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
imported>Tom.Reding
m (fix vauthors)
 
Line 1: Line 1:
{{Infobox_gene}}
{{Infobox_gene}}
'''Zinc finger protein Aiolos''' also known as '''Ikaros family zinc finger protein 3''' is a [[protein]] that in humans is encoded by the ''IKZF3'' [[gene]].<ref name="pmid9155026">{{cite journal |vauthors=Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, Gonzales E, Wu P, Neben S, Georgopoulos K | title = Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation | journal = EMBO J | volume = 16 | issue = 8 | pages = 2004–13 |date=Jun 1997 | pmid = 9155026 | pmc = 1169803 | doi = 10.1093/emboj/16.8.2004 }}</ref><ref name="pmid10552935">{{cite journal |vauthors=Hosokawa Y, Maeda Y, Takahashi E, Suzuki M, Seto M | title = Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping | journal = Genomics | volume = 61 | issue = 3 | pages = 326–9 |date=Feb 2000 | pmid = 10552935 | pmc =  | doi = 10.1006/geno.1999.5949 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IKZF3 IKAROS family zinc finger 3 (Aiolos)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22806| accessdate = }}</ref>
'''Zinc finger protein Aiolos''' also known as '''Ikaros family zinc finger protein 3''' is a [[protein]] that in humans is encoded by the ''IKZF3'' [[gene]].<ref name="pmid9155026">{{cite journal | vauthors = Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, Gonzales E, Wu P, Neben S, Georgopoulos K | title = Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation | journal = The EMBO Journal | volume = 16 | issue = 8 | pages = 2004–13 | date = April 1997 | pmid = 9155026 | pmc = 1169803 | doi = 10.1093/emboj/16.8.2004 }}</ref><ref name="pmid10552935">{{cite journal | vauthors = Hosokawa Y, Maeda Y, Takahashi EI, Suzuki M, Seto M | title = Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping | journal = Genomics | volume = 61 | issue = 3 | pages = 326–9 | date = November 1999 | pmid = 10552935 | pmc =  | doi = 10.1006/geno.1999.5949 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IKZF3 IKAROS family zinc finger 3 (Aiolos)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22806| accessdate = }}</ref>


== Function ==
== Function ==
Line 8: Line 8:
== Interactions ==
== Interactions ==


IKZF3 has been shown to [[Protein-protein interaction|interact]] with [[BCL2-like 1 (gene)|BCL2-like 1]]<ref name="pmid11714801">{{cite journal |vauthors=Rebollo A, Ayllón V, Fleischer A, Martínez CA, Zaballos A | title = The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis | journal = J. Immunol. | volume = 167 | issue = 11 | pages = 6366–73 |date=December 2001 | pmid = 11714801 | doi = 10.4049/jimmunol.167.11.6366| url = | issn = }}</ref> and [[HRAS]].<ref name="pmid10369681">{{cite journal |vauthors=Romero F, Martínez-A C, Camonis J, Rebollo A | title = Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization | journal = EMBO J. | volume = 18 | issue = 12 | pages = 3419–30 |date=June 1999 | pmid = 10369681 | pmc = 1171421 | doi = 10.1093/emboj/18.12.3419 | url = | issn = }}</ref>
IKZF3 has been shown to [[Protein-protein interaction|interact]] with [[BCL2-like 1 (gene)|BCL2-like 1]]<ref name="pmid11714801">{{cite journal | vauthors = Rebollo A, Ayllón V, Fleischer A, Martínez CA, Zaballos A | title = The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis | journal = Journal of Immunology | volume = 167 | issue = 11 | pages = 6366–73 | date = December 2001 | pmid = 11714801 | doi = 10.4049/jimmunol.167.11.6366 }}</ref> and [[HRAS]].<ref name="pmid10369681">{{cite journal | vauthors = Romero F, Martínez-A C, Camonis J, Rebollo A | title = Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization | journal = The EMBO Journal | volume = 18 | issue = 12 | pages = 3419–30 | date = June 1999 | pmid = 10369681 | pmc = 1171421 | doi = 10.1093/emboj/18.12.3419 }}</ref>


== References ==
== References ==
{{reflist}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Sun J, Matthias G, Mihatsch MJ, Georgopoulos K, Matthias P | title = Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice | journal = Journal of Immunology | volume = 170 | issue = 4 | pages = 1699–706 | date = February 2003 | pmid = 12574333 | doi = 10.4049/jimmunol.170.4.1699 }}
| citations =
* {{cite journal | vauthors = Schmitt C, Tonnelle C, Dalloul A, Chabannon C, Debré P, Rebollo A | title = Aiolos and Ikaros: regulators of lymphocyte development, homeostasis and lymphoproliferation | journal = Apoptosis | volume = 7 | issue = 3 | pages = 277–84 | date = June 2002 | pmid = 11997672 | doi = 10.1023/A:1015372322419 }}
* {{cite journal |vauthors=Sun J, Matthias G, Mihatsch MJ, Georgopoulos K, Matthias P | title = Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice | journal = J. Immunol. | volume = 170 | issue = 4 | pages = 1699–706 |date=February 2003 | pmid = 12574333 | doi = 10.4049/jimmunol.170.4.1699| url = | issn = }}
* {{cite journal | vauthors = Wang JH, Avitahl N, Cariappa A, Friedrich C, Ikeda T, Renold A, Andrikopoulos K, Liang L, Pillai S, Morgan BA, Georgopoulos K | title = Aiolos regulates B cell activation and maturation to effector state | journal = Immunity | volume = 9 | issue = 4 | pages = 543–53 | date = October 1998 | pmid = 9806640 | doi = 10.1016/S1074-7613(00)80637-8 }}
*{{cite journal   |vauthors=Schmitt C, Tonnelle C, Dalloul A, etal |title=Aiolos and Ikaros: regulators of lymphocyte development, homeostasis and lymphoproliferation. |journal=Apoptosis |volume=7 |issue= 3 |pages= 277–84 |year= 2003 |pmid= 11997672 |doi=10.1023/A:1015372322419 }}
* {{cite journal | vauthors = Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K | title = Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes | journal = Immunity | volume = 10 | issue = 3 | pages = 345–55 | date = March 1999 | pmid = 10204490 | doi = 10.1016/S1074-7613(00)80034-5 }}
*{{cite journal   |vauthors=Wang JH, Avitahl N, Cariappa A, etal |title=Aiolos regulates B cell activation and maturation to effector state. |journal=Immunity |volume=9 |issue= 4 |pages= 543–53 |year= 1998 |pmid= 9806640 |doi=10.1016/S1074-7613(00)80637-8 }}
* {{cite journal | vauthors = Koipally J, Renold A, Kim J, Georgopoulos K | title = Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes | journal = The EMBO Journal | volume = 18 | issue = 11 | pages = 3090–100 | date = June 1999 | pmid = 10357820 | pmc = 1171390 | doi = 10.1093/emboj/18.11.3090 }}
*{{cite journal   |vauthors=Kim J, Sif S, Jones B, etal |title=Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. |journal=Immunity |volume=10 |issue= 3 |pages= 345–55 |year= 1999 |pmid= 10204490 |doi=10.1016/S1074-7613(00)80034-5 }}
* {{cite journal | vauthors = Romero F, Martínez-A C, Camonis J, Rebollo A | title = Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization | journal = The EMBO Journal | volume = 18 | issue = 12 | pages = 3419–30 | date = June 1999 | pmid = 10369681 | pmc = 1171421 | doi = 10.1093/emboj/18.12.3419 }}
*{{cite journal |vauthors=Koipally J, Renold A, Kim J, Georgopoulos K |title=Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes. |journal=EMBO J. |volume=18 |issue= 11 |pages= 3090–100 |year= 1999 |pmid= 10357820 |doi= 10.1093/emboj/18.11.3090 | pmc=1171390 }}
* {{cite journal | vauthors = Koipally J, Georgopoulos K | title = Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity | journal = The Journal of Biological Chemistry | volume = 275 | issue = 26 | pages = 19594–602 | date = June 2000 | pmid = 10766745 | doi = 10.1074/jbc.M000254200 }}
*{{cite journal |vauthors=Romero F, Martínez-A C, Camonis J, Rebollo A |title=Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization. |journal=EMBO J. |volume=18 |issue= 12 |pages= 3419–30 |year= 1999 |pmid= 10369681 |doi= 10.1093/emboj/18.12.3419 | pmc=1171421 }}
* {{cite journal | vauthors = Perdomo J, Holmes M, Chong B, Crossley M | title = Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities | journal = The Journal of Biological Chemistry | volume = 275 | issue = 49 | pages = 38347–54 | date = December 2000 | pmid = 10978333 | doi = 10.1074/jbc.M005457200 }}
*{{cite journal |vauthors=Koipally J, Georgopoulos K |title=Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity. |journal=J. Biol. Chem. |volume=275 |issue= 26 |pages= 19594–602 |year= 2000 |pmid= 10766745 |doi= 10.1074/jbc.M000254200 }}
* {{cite journal | vauthors = Rebollo A, Ayllón V, Fleischer A, Martínez CA, Zaballos A | title = The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis | journal = Journal of Immunology | volume = 167 | issue = 11 | pages = 6366–73 | date = December 2001 | pmid = 11714801 | doi = 10.4049/jimmunol.167.11.6366 }}
*{{cite journal |vauthors=Perdomo J, Holmes M, Chong B, Crossley M |title=Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities. |journal=J. Biol. Chem. |volume=275 |issue= 49 |pages= 38347–54 |year= 2001 |pmid= 10978333 |doi= 10.1074/jbc.M005457200 }}
* {{cite journal | vauthors = Liippo J, Nera KP, Veistinen E, Lähdesmäki A, Postila V, Kimby E, Riikonen P, Hammarström L, Pelkonen J, Lassila O | title = Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene | journal = European Journal of Immunology | volume = 31 | issue = 12 | pages = 3469–74 | date = December 2001 | pmid = 11745366 | doi = 10.1002/1521-4141(200112)31:12<3469::AID-IMMU3469>3.0.CO;2-G }}
*{{cite journal   |vauthors=Rebollo A, Ayllón V, Fleischer A, etal |title=The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis. |journal=J. Immunol. |volume=167 |issue= 11 |pages= 6366–73 |year= 2002 |pmid= 11714801 |doi= 10.4049/jimmunol.167.11.6366}}
* {{cite journal | vauthors = Nakase K, Ishimaru F, Fujii K, Tabayashi T, Kozuka T, Sezaki N, Matsuo Y, Harada M | title = Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia | journal = Experimental Hematology | volume = 30 | issue = 4 | pages = 313–7 | date = April 2002 | pmid = 11937265 | doi = 10.1016/S0301-472X(01)00796-2 }}
*{{cite journal   |vauthors=Liippo J, Nera KP, Veistinen E, etal |title=Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene. |journal=Eur. J. Immunol. |volume=31 |issue= 12 |pages= 3469–74 |year= 2002 |pmid= 11745366 |doi=10.1002/1521-4141(200112)31:12<3469::AID-IMMU3469>3.0.CO;2-G }}
* {{cite journal | vauthors = Koipally J, Georgopoulos K | title = A molecular dissection of the repression circuitry of Ikaros | journal = The Journal of Biological Chemistry | volume = 277 | issue = 31 | pages = 27697–705 | date = August 2002 | pmid = 12015313 | doi = 10.1074/jbc.M201694200 }}
*{{cite journal   |vauthors=Nakase K, Ishimaru F, Fujii K, etal |title=Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia. |journal=Exp. Hematol. |volume=30 |issue= 4 |pages= 313–7 |year= 2002 |pmid= 11937265 |doi=10.1016/S0301-472X(01)00796-2 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal |vauthors=Koipally J, Georgopoulos K |title=A molecular dissection of the repression circuitry of Ikaros. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 27697–705 |year= 2002 |pmid= 12015313 |doi= 10.1074/jbc.M201694200 }}
* {{cite journal | vauthors = Antica M, Dubravcic K, Weber I, Raic L, Labar B, Batinic D | title = A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia | journal = Haematologica | volume = 92 | issue = 2 | pages = 260–1 | date = February 2007 | pmid = 17296582 | doi = 10.3324/haematol.10753 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
* {{cite journal | vauthors = Ghadiri A, Duhamel M, Fleischer A, Reimann A, Dessauge F, Rebollo A | title = Critical function of Ikaros in controlling Aiolos gene expression | journal = FEBS Letters | volume = 581 | issue = 8 | pages = 1605–16 | date = April 2007 | pmid = 17383641 | doi = 10.1016/j.febslet.2007.03.025 }}
*{{cite journal  |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
* {{cite journal | vauthors = Caballero R, Setien F, Lopez-Serra L, Boix-Chornet M, Fraga MF, Ropero S, Megias D, Alaminos M, Sanchez-Tapia EM, Montoya MC, Esteller M, Gonzalez-Sarmiento R, Ballestar E | title = Combinatorial effects of splice variants modulate function of Aiolos | journal = Journal of Cell Science | volume = 120 | issue = Pt 15 | pages = 2619–30 | date = August 2007 | pmid = 17646674 | doi = 10.1242/jcs.007344 }}
*{{cite journal   |vauthors=Antica M, Dubravcic K, Weber I, etal |title=A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia. |journal=Haematologica |volume=92 |issue= 2 |pages= 260–1 |year= 2007 |pmid= 17296582 |doi=10.3324/haematol.10753 }}
*{{cite journal   |vauthors=Ghadiri A, Duhamel M, Fleischer A, etal |title=Critical function of Ikaros in controlling Aiolos gene expression. |journal=FEBS Lett. |volume=581 |issue= 8 |pages= 1605–16 |year= 2007 |pmid= 17383641 |doi= 10.1016/j.febslet.2007.03.025 }}
*{{cite journal   |vauthors=Caballero R, Setien F, Lopez-Serra L, etal |title=Combinatorial effects of splice variants modulate function of Aiolos. |journal=J. Cell Sci. |volume=120 |issue= Pt 15 |pages= 2619–30 |year= 2007 |pmid= 17646674 |doi= 10.1242/jcs.007344 }}
}}
{{refend}}
{{refend}}


Line 42: Line 38:
{{NLM content}}
{{NLM content}}
{{Transcription factors|g2}}
{{Transcription factors|g2}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = no
| update_citations = yes
}}


[[Category:Transcription factors]]
[[Category:Transcription factors]]


{{gene-17-stub}}
{{gene-17-stub}}

Latest revision as of 02:35, 4 January 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene.[1][2][3]

Function

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.[3]

Interactions

IKZF3 has been shown to interact with BCL2-like 1[4] and HRAS.[5]

References

  1. ↑ Morgan B, Sun L, Avitahl N, Andrikopoulos K, Ikeda T, Gonzales E, Wu P, Neben S, Georgopoulos K (April 1997). "Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation". The EMBO Journal. 16 (8): 2004–13. doi:10.1093/emboj/16.8.2004. PMC 1169803. PMID 9155026.
  2. ↑ Hosokawa Y, Maeda Y, Takahashi EI, Suzuki M, Seto M (November 1999). "Human aiolos, an ikaros-related zinc finger DNA binding protein: cDNA cloning, tissue expression pattern, and chromosomal mapping". Genomics. 61 (3): 326–9. doi:10.1006/geno.1999.5949. PMID 10552935.
  3. ↑ 3.0 3.1 "Entrez Gene: IKZF3 IKAROS family zinc finger 3 (Aiolos)".
  4. ↑ Rebollo A, Ayllón V, Fleischer A, Martínez CA, Zaballos A (December 2001). "The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis". Journal of Immunology. 167 (11): 6366–73. doi:10.4049/jimmunol.167.11.6366. PMID 11714801.
  5. ↑ Romero F, Martínez-A C, Camonis J, Rebollo A (June 1999). "Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization". The EMBO Journal. 18 (12): 3419–30. doi:10.1093/emboj/18.12.3419. PMC 1171421. PMID 10369681.

Further reading

  • Sun J, Matthias G, Mihatsch MJ, Georgopoulos K, Matthias P (February 2003). "Lack of the transcriptional coactivator OBF-1 prevents the development of systemic lupus erythematosus-like phenotypes in Aiolos mutant mice". Journal of Immunology. 170 (4): 1699–706. doi:10.4049/jimmunol.170.4.1699. PMID 12574333.
  • Schmitt C, Tonnelle C, Dalloul A, Chabannon C, Debré P, Rebollo A (June 2002). "Aiolos and Ikaros: regulators of lymphocyte development, homeostasis and lymphoproliferation". Apoptosis. 7 (3): 277–84. doi:10.1023/A:1015372322419. PMID 11997672.
  • Wang JH, Avitahl N, Cariappa A, Friedrich C, Ikeda T, Renold A, Andrikopoulos K, Liang L, Pillai S, Morgan BA, Georgopoulos K (October 1998). "Aiolos regulates B cell activation and maturation to effector state". Immunity. 9 (4): 543–53. doi:10.1016/S1074-7613(00)80637-8. PMID 9806640.
  • Kim J, Sif S, Jones B, Jackson A, Koipally J, Heller E, Winandy S, Viel A, Sawyer A, Ikeda T, Kingston R, Georgopoulos K (March 1999). "Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes". Immunity. 10 (3): 345–55. doi:10.1016/S1074-7613(00)80034-5. PMID 10204490.
  • Koipally J, Renold A, Kim J, Georgopoulos K (June 1999). "Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes". The EMBO Journal. 18 (11): 3090–100. doi:10.1093/emboj/18.11.3090. PMC 1171390. PMID 10357820.
  • Romero F, Martínez-A C, Camonis J, Rebollo A (June 1999). "Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization". The EMBO Journal. 18 (12): 3419–30. doi:10.1093/emboj/18.12.3419. PMC 1171421. PMID 10369681.
  • Koipally J, Georgopoulos K (June 2000). "Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity". The Journal of Biological Chemistry. 275 (26): 19594–602. doi:10.1074/jbc.M000254200. PMID 10766745.
  • Perdomo J, Holmes M, Chong B, Crossley M (December 2000). "Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities". The Journal of Biological Chemistry. 275 (49): 38347–54. doi:10.1074/jbc.M005457200. PMID 10978333.
  • Rebollo A, Ayllón V, Fleischer A, Martínez CA, Zaballos A (December 2001). "The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis". Journal of Immunology. 167 (11): 6366–73. doi:10.4049/jimmunol.167.11.6366. PMID 11714801.
  • Liippo J, Nera KP, Veistinen E, Lähdesmäki A, Postila V, Kimby E, Riikonen P, Hammarström L, Pelkonen J, Lassila O (December 2001). "Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene". European Journal of Immunology. 31 (12): 3469–74. doi:10.1002/1521-4141(200112)31:12<3469::AID-IMMU3469>3.0.CO;2-G. PMID 11745366.
  • Nakase K, Ishimaru F, Fujii K, Tabayashi T, Kozuka T, Sezaki N, Matsuo Y, Harada M (April 2002). "Overexpression of novel short isoforms of Helios in a patient with T-cell acute lymphoblastic leukemia". Experimental Hematology. 30 (4): 313–7. doi:10.1016/S0301-472X(01)00796-2. PMID 11937265.
  • Koipally J, Georgopoulos K (August 2002). "A molecular dissection of the repression circuitry of Ikaros". The Journal of Biological Chemistry. 277 (31): 27697–705. doi:10.1074/jbc.M201694200. PMID 12015313.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Antica M, Dubravcic K, Weber I, Raic L, Labar B, Batinic D (February 2007). "A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia". Haematologica. 92 (2): 260–1. doi:10.3324/haematol.10753. PMID 17296582.
  • Ghadiri A, Duhamel M, Fleischer A, Reimann A, Dessauge F, Rebollo A (April 2007). "Critical function of Ikaros in controlling Aiolos gene expression". FEBS Letters. 581 (8): 1605–16. doi:10.1016/j.febslet.2007.03.025. PMID 17383641.
  • Caballero R, Setien F, Lopez-Serra L, Boix-Chornet M, Fraga MF, Ropero S, Megias D, Alaminos M, Sanchez-Tapia EM, Montoya MC, Esteller M, Gonzalez-Sarmiento R, Ballestar E (August 2007). "Combinatorial effects of splice variants modulate function of Aiolos". Journal of Cell Science. 120 (Pt 15): 2619–30. doi:10.1242/jcs.007344. PMID 17646674.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Retrieved from "https://www.wikidoc.org/index.php?title=IKZF3&oldid=1529212"