HOXC13

Homeobox C13
Identifiers
Symbols	HOXC13 ; HOX3; HOX3G
External IDs	Template:OMIM5 Template:MGI HomoloGene: 7770
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Homeobox C13, also known as HOXC13, is a human gene.

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.

See also

• Homeobox

Further reading

• Godwin AR, Capecchi MR (2000). "Hair defects in Hoxc13 mutant mice". J. Investig. Dermatol. Symp. Proc. 4 (3): 244–7. PMID 10674376.
• Panagopoulos I, Isaksson M, Billström R; et al. (2003). "Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13)". Genes Chromosomes Cancer. 36 (1): 107–12. doi:10.1002/gcc.10139. PMID 12461755.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scott MP (1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. PMID 1358459.
• McAlpine PJ, Shows TB (1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. PMID 1973146.
• Acampora D, D'Esposito M, Faiella A; et al. (1990). "The human HOX gene family". Nucleic Acids Res. 17 (24): 10385–402. PMID 2574852.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rabin M, Ferguson-Smith A, Hart CP, Ruddle FH (1987). "Cognate homeo-box loci mapped on homologous human and mouse chromosomes". Proc. Natl. Acad. Sci. U.S.A. 83 (23): 9104–8. PMID 2878432.CS1 maint: Multiple names: authors list (link)
• Apiou F, Flagiello D, Cillo C; et al. (1996). "Fine mapping of human HOX gene clusters". Cytogenet. Cell Genet. 73 (1–2): 114–5. PMID 8646877.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Flagiello D, Gibaud A, Dutrillaux B; et al. (1997). "Distinct patterns of all-trans retinoic acid dependent expression of HOXB and HOXC homeogenes in human embryonal and small-cell lung carcinoma cell lines". FEBS Lett. 415 (3): 263–7. PMID 9357979.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• de Stanchina E, Gabellini D, Norio P; et al. (2000). "Selection of homeotic proteins for binding to a human DNA replication origin". J. Mol. Biol. 299 (3): 667–80. doi:10.1006/jmbi.2000.3782. PMID 10835276.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kulessa H, Turk G, Hogan BL (2001). "Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle". EMBO J. 19 (24): 6664–74. doi:10.1093/emboj/19.24.6664. PMID 11118201.CS1 maint: Multiple names: authors list (link)
• Kosaki K, Kosaki R, Suzuki T; et al. (2002). "Complete mutation analysis panel of the 39 human HOX genes". Teratology. 65 (2): 50–62. doi:10.1002/tera.10009. PMID 11857506.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pruett ND, Tkatchenko TV, Jave-Suarez L; et al. (2005). "Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13". J. Biol. Chem. 279 (49): 51524–33. doi:10.1074/jbc.M404331200. PMID 15385554.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• HOXC13+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.