Kinase insert domain receptor

	Kinase insert domain receptor (a type III receptor tyrosine kinase)
	Identifiers
Symbol(s)	KDR; CD309; FLK1; VEGFR; VEGFR2
External IDs	OMIM: 191306 MGI: 96683 Homologene: 55639
Gene ontology
Molecular Function:	• nucleotide binding; • receptor activity; • vascular endothelial growth factor receptor activity; • protein binding; • ATP binding; • transferase activity;
Cellular Component:	• integral to plasma membrane; • membrane;
Biological Process:	• angiogenesis; • vasculogenesis; • protein amino acid phosphorylation; • transmembrane receptor protein tyrosine kinase signaling pathway; • multicellular organismal development; • cell migration; • hemopoiesis; • cell fate commitment; • endothelial cell differentiation;
	RNA expression pattern
	250px More reference expression data
	Orthologs

Kinase insert domain receptor (a type III receptor tyrosine kinase), also known as KDR, is a human gene.

Petrova TV, Makinen T, Alitalo K (1999). "Signaling via vascular endothelial growth factor receptors.". Exp. Cell Res. 253 (1): 117-30. doi:10.1006/excr.1999.4707. PMID 10579917.
Sato Y, Kanno S, Oda N, et al. (2000). "Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction.". Ann. N. Y. Acad. Sci. 902: 201-5; discussion 205-7. PMID 10865839.
Zachary I, Gliki G (2001). "Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family.". Cardiovasc. Res. 49 (3): 568-81. PMID 11166270.
Vené R, Benelli R, Noonan DM, Albini A (2001). "HIV-Tat dependent chemotaxis and invasion, key aspects of tat mediated pathogenesis.". Clin. Exp. Metastasis 18 (7): 533-8. PMID 11688957.
Lenton K (2003). "VEGFR-2 (KDR/Flk-1).". J. Biol. Regul. Homeost. Agents 16 (3): 227-32. PMID 12456025.
Matsumoto T, Mugishima H (2006). "Signal transduction via vascular endothelial growth factor (VEGF) receptors and their roles in atherogenesis.". J. Atheroscler. Thromb. 13 (3): 130-5. PMID 16835467.

See also