CD11c

integrin, alpha X (complement component 3 receptor 4 subunit)
Identifiers
Symbol	ITGAX
Alt. Symbols	CD11C
Entrez	3687
HUGO	6152
OMIM	151510
RefSeq	NM_000887
UniProt	P20702
Other data
Locus	Chr. 16 p11.2

CD11c is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.

See also

• Integrin

External links

• MeSH CD11c+Antigens