CD61: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
m (Bot: HTTP→HTTPS)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Integrin beta-3''' (β3) or '''CD61''' is a [[protein]] that in humans is encoded by the ''ITGB3'' [[gene]].<ref name="pmid2454952">{{cite journal |vauthors=Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, Kaos FT, Schwartz E, Phillips D, Bennett JS | title = Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa | journal = J Clin Invest | volume = 81 | issue = 6 | pages = 1993–8 |date=August 1988 | pmid = 2454952 | pmc = 442653 | doi = 10.1172/JCI113548 |display-authors=etal}}</ref>  '''CD61''' is a [[cluster of differentiation]] found on [[thrombocyte]]s.<ref name="HeemskerkMattheij2013">{{cite journal|last1=Heemskerk|first1=J. W. M.|last2=Mattheij|first2=N. J. A.|last3=Cosemans|first3=J. M. E. M.|title=Platelet-based coagulation: different populations, different functions|journal=Journal of Thrombosis and Haemostasis|volume=11|issue=1|year=2013|pages=2–16|issn=1538-7933|doi=10.1111/jth.12045}}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
==Structure and function==
{{GNF_Protein_box
The ITGB3 protein product is the integrin beta chain beta 3. [[Integrins]] are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface-mediated signaling.<ref>{{cite web | title = Entrez Gene: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3690| accessdate = }}</ref>
| image = PBB_Protein_ITGB3_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1jv2.
| PDB = {{PDB2|1jv2}}, {{PDB2|1l5g}}, {{PDB2|1m1x}}, {{PDB2|1m8o}}, {{PDB2|1txv}}, {{PDB2|1ty3}}, {{PDB2|1ty5}}, {{PDB2|1ty6}}, {{PDB2|1ty7}}, {{PDB2|1tye}}, {{PDB2|1u8c}}
| Name = Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
| HGNCid = 6156
| Symbol = ITGB3
| AltSymbols =; CD61; GP3A; GPIIIa
| OMIM = 173470
| ECnumber = 
| Homologene = 55444
| MGIid = 96612
| GeneAtlas_image1 = PBB_GE_ITGB3_204628_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_ITGB3_204625_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_ITGB3_204626_s_at_tn.png
<!-- The Following entry is a time stamp of the last bot update. It is typically hidden data -->
| DateOfBotUpdate = 07:30, 9 October 2007 (UTC)
| Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005178 |text = integrin binding}} {{GNF_GO|id=GO:0042802 |text = identical protein binding}}
| Component = {{GNF_GO|id=GO:0008305 |text = integrin complex}} {{GNF_GO|id=GO:0009897 |text = external side of plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007044 |text = cell-substrate junction assembly}} {{GNF_GO|id=GO:0007155 |text = cell adhesion}} {{GNF_GO|id=GO:0007160 |text = cell-matrix adhesion}} {{GNF_GO|id=GO:0007229 |text = integrin-mediated signaling pathway}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007596 |text = blood coagulation}} {{GNF_GO|id=GO:0030334 |text = regulation of cell migration}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3690
    | Hs_Ensembl = ENSG00000056345
    | Hs_RefseqProtein = NP_000203
    | Hs_RefseqmRNA = NM_000212
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 42686207
    | Hs_GenLoc_end = 42745076
    | Hs_Uniprot = P05106
    | Mm_EntrezGene = 16416
    | Mm_Ensembl = ENSMUSG00000020689
    | Mm_RefseqmRNA = NM_016780
    | Mm_RefseqProtein = NP_058060
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 104424146
    | Mm_GenLoc_end = 104483465
    | Mm_Uniprot = P97483
  }}
}}
'''Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)''', also known as '''ITGB3''', is a human [[gene]]. '''CD61''' is a [[cluster of differentiation]] found on [[thrombocyte]]s.


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
==Role in endometriosis==
{{PBB_Summary
Defectively expressed β3 integrin subunit has been correlated with presence of [[endometriosis]], and has been suggested as a putative marker of this condition.<ref>{{Cite journal | last1 = May | first1 = K. E. | last2 = Villar | first2 = J. | last3 = Kirtley | first3 = S. | last4 = Kennedy | first4 = S. H. | last5 = Becker | first5 = C. M. | title = Endometrial alterations in endometriosis: A systematic review of putative biomarkers | doi = 10.1093/humupd/dmr013 | journal = Human Reproduction Update | volume = 17 | issue = 5 | pages = 637–653 | year = 2011 | pmid =  21672902| pmc = }}</ref>
| section_title =  
 
| summary_text = The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.<ref>{{cite web | title = Entrez Gene: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3690| accessdate = }}</ref>
==Interactions==
}}
CD61 has been shown to [[Protein-protein interaction|interact]] with [[PTK2]],<ref name=pmid11927607>{{cite journal |last=Eliceiri |first=Brian P |authorlink= |author2=Puente Xose S |author3=Hood John D |author4=Stupack Dwayne G |author5=Schlaepfer David D |author6=Huang Xiaozhu Z |author7=Sheppard Dean |author8=Cheresh David A  |date=April 2002  |title=Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling |journal=J. Cell Biol. |volume=157 |issue=1 |pages=149–60 |publisher= |location = United States| issn = 0021-9525| pmid = 11927607 |doi = 10.1083/jcb.200109079 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=2173263 }}</ref><ref name=pmid9169439>{{cite journal |last=Chung |first=J |authorlink= |author2=Gao A G|author3=Frazier W A |date=June 1997  |title=Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3 |journal=J. Biol. Chem. |volume=272 |issue=23 |pages=14740–6 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9169439 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.272.23.14740 }}</ref> [[ITGB3BP]],<ref name=pmid11864709>{{cite journal |last=Fujimoto |first=Tetsuro-Takahiro |authorlink= |author2=Katsutani Shinya |author3=Shimomura Takeshi |author4=Fujimura Kingo  |date=January 2002  |title=Novel alternatively spliced form of beta(3)-endonexin |journal=Thromb. Res. |volume=105 |issue=1 |pages=63–70 |publisher= |location = United States| issn = 0049-3848| pmid = 11864709 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1016/S0049-3848(01)00405-4 }}</ref><ref name=pmid7593198>{{cite journal |last=Shattil |first=S J |authorlink= |author2=O'Toole T|author3=Eigenthaler M|author4=Thon V|author5=Williams M|author6=Babior B M|author7=Ginsberg M H |date=November 1995  |title=Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit |journal=J. Cell Biol. |volume=131 |issue=3 |pages=807–16 |publisher= |location = UNITED STATES| issn = 0021-9525| pmid = 7593198 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1083/jcb.131.3.807 |pmc=2120613 }}</ref> [[TLN1]]<ref name=pmid10497223>{{cite journal |last=Patil |first=S |authorlink= |author2=Jedsadayanmata A|author3=Wencel-Drake J D|author4=Wang W|author5=Knezevic I|author6=Lam S C |date=October 1999  |title=Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding functions. The talin n-terminal head domain interacts with the membrane-proximal region of the beta(3) cytoplasmic tail |journal=J. Biol. Chem. |volume=274 |issue=40 |pages=28575–83 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10497223 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.274.40.28575 }}</ref><ref name=pmid11932255>{{cite journal |last=Calderwood |first=David A |authorlink= |author2=Yan Boxu |author3=de Pereda Jose M |author4=Alvarez Begoña García |author5=Fujioka Yosuke |author6=Liddington Robert C |author7=Ginsberg Mark H  |date=June 2002  |title=The phosphotyrosine binding-like domain of talin activates integrins |journal=J. Biol. Chem. |volume=277 |issue=24 |pages=21749–58 |publisher= |location = United States| issn = 0021-9258| pmid = 11932255 |doi = 10.1074/jbc.M111996200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[CIB1]].<ref name=pmid9030514>{{cite journal |last=Naik |first=U P |authorlink= |author2=Patel P M|author3=Parise L V |date=February 1997  |title=Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain |journal=J. Biol. Chem. |volume=272 |issue=8 |pages=4651–4 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9030514 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1074/jbc.272.8.4651 }}</ref>


==See also==
==See also==
Line 62: Line 15:


==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
*{{cite journal  | author=Bray PF |title=Inherited diseases of platelet glycoproteins: considerations for rapid molecular characterization. |journal=Thromb. Haemost. |volume=72 |issue= 4 |pages= 492–502 |year= 1995 |pmid= 7878622 |doi=  }}
| citations =
*{{cite journal  | author=Bennett JS |title=Platelet-fibrinogen interactions. |journal=Ann. N. Y. Acad. Sci. |volume=936 |issue=  |pages= 340–54 |year= 2001 |pmid= 11460491 |doi=10.1111/j.1749-6632.2001.tb03521.x }}
*{{cite journal  | author=Bray PF |title=Inherited diseases of platelet glycoproteins: considerations for rapid molecular characterization. |journal=Thromb. Haemost. |volume=72 |issue= 4 |pages= 492-502 |year= 1995 |pmid= 7878622 |doi=  }}
*{{cite journal  |vauthors=Sajid M, Stouffer GA |title=The role of alpha(v)beta3 integrins in vascular healing. |journal=Thromb. Haemost. |volume=87 |issue= 2 |pages= 187–93 |year= 2002 |pmid= 11858476 |doi=  }}
*{{cite journal  | author=Bennett JS |title=Platelet-fibrinogen interactions. |journal=Ann. N. Y. Acad. Sci. |volume=936 |issue=  |pages= 340-54 |year= 2001 |pmid= 11460491 |doi=  }}
*{{cite journal  |vauthors=Quinn MJ, Byzova TV, Qin J |title=Integrin alphaIIbbeta3 and its antagonism. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=23 |issue= 6 |pages= 945–52 |year= 2004 |pmid= 12637342 |doi= 10.1161/01.ATV.0000066686.46338.F1 |display-authors=etal}}
*{{cite journal  | author=Sajid M, Stouffer GA |title=The role of alpha(v)beta3 integrins in vascular healing. |journal=Thromb. Haemost. |volume=87 |issue= 2 |pages= 187-93 |year= 2002 |pmid= 11858476 |doi=  }}
*{{cite journal  |vauthors=Charakida M, Tousoulis D, Stefanadis C, Toutouzas P |title=The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease. |journal=Italian Heart Journal |volume=4 |issue= 1 |pages= 17–22 |year= 2003 |pmid= 12690916 |doi=  }}
*{{cite journal  | author=Quinn MJ, Byzova TV, Qin J, ''et al.'' |title=Integrin alphaIIbbeta3 and its antagonism. |journal=Arterioscler. Thromb. Vasc. Biol. |volume=23 |issue= 6 |pages= 945-52 |year= 2004 |pmid= 12637342 |doi= 10.1161/01.ATV.0000066686.46338.F1 }}
*{{cite journal  |vauthors=Smith FB, Connor JM, Lee AJ |title=Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease. |journal=Thromb. Res. |volume=112 |issue= 4 |pages= 209–16 |year= 2004 |pmid= 14987913 |doi= 10.1016/j.thromres.2003.11.010 |display-authors=etal}}
*{{cite journal  | author=Charakida M, Tousoulis D, Stefanadis C, Toutouzas P |title=The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease. |journal=Italian heart journal : official journal of the Italian Federation of Cardiology |volume=4 |issue= 1 |pages= 17-22 |year= 2003 |pmid= 12690916 |doi=  }}
*{{cite journal  | author=Fullard JF |title=The role of the platelet glycoprotein IIb/IIIa in thrombosis and haemostasis. |journal=Curr. Pharm. Des. |volume=10 |issue= 14 |pages= 1567–76 |year= 2004 |pmid= 15134555 |doi=10.2174/1381612043384682 }}
*{{cite journal  | author=Smith FB, Connor JM, Lee AJ, ''et al.'' |title=Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease. |journal=Thromb. Res. |volume=112 |issue= 4 |pages= 209-16 |year= 2004 |pmid= 14987913 |doi= 10.1016/j.thromres.2003.11.010 }}
*{{cite journal  |vauthors=Cacciari B, Spalluto G |title=Non peptidic alphavbeta3 antagonists: recent developments. |journal=Curr. Med. Chem. |volume=12 |issue= 1 |pages= 51–70 |year= 2005 |pmid= 15638730 |doi=  10.2174/0929867053363522}}
*{{cite journal  | author=Fullard JF |title=The role of the platelet glycoprotein IIb/IIIa in thrombosis and haemostasis. |journal=Curr. Pharm. Des. |volume=10 |issue= 14 |pages= 1567-76 |year= 2004 |pmid= 15134555 |doi=  }}
*{{cite journal  |vauthors=Watson SP, Auger JM, McCarty OJ, Pearce AC |title=GPVI and integrin alphaIIb beta3 signaling in platelets. |journal=J. Thromb. Haemost. |volume=3 |issue= 8 |pages= 1752–62 |year= 2005 |pmid= 16102042 |doi= 10.1111/j.1538-7836.2005.01429.x }}
*{{cite journal  | author=Cacciari B, Spalluto G |title=Non peptidic alphavbeta3 antagonists: recent developments. |journal=Curr. Med. Chem. |volume=12 |issue= 1 |pages= 51-70 |year= 2005 |pmid= 15638730 |doi=  }}
*{{cite journal  | author=Bennett JS |title=Structure and function of the platelet integrin alphaIIbbeta3. |journal=J. Clin. Invest. |volume=115 |issue= 12 |pages= 3363–9 |year= 2006 |pmid= 16322781 |doi= 10.1172/JCI26989 | pmc=1297263 }}
*{{cite journal  | author=Watson SP, Auger JM, McCarty OJ, Pearce AC |title=GPVI and integrin alphaIIb beta3 signaling in platelets. |journal=J. Thromb. Haemost. |volume=3 |issue= 8 |pages= 1752-62 |year= 2005 |pmid= 16102042 |doi= 10.1111/j.1538-7836.2005.01429.x }}
*{{cite journal  | author=Bennett JS |title=Structure and function of the platelet integrin alphaIIbbeta3. |journal=J. Clin. Invest. |volume=115 |issue= 12 |pages= 3363-9 |year= 2006 |pmid= 16322781 |doi= 10.1172/JCI26989 }}
}}
{{refend}}
{{refend}}
{{protein-stub}}


==External links==
==External links==
* {{MeshName|CD61+Antigens}}
* {{MeshName|CD61+Antigens}}
* [http://cmkb.cellmigration.org/report.cgi?report=orth_overview&orth_acc=co00002323 ITGB3] Info with links in the [http://www.cellmigration.org/index.shtml Cell Migration Gateway]
* {{UCSC gene info|ITGB3}}


{{protein-stub}}
{{PDB Gallery|geneid=3690}}
{{Clusters of differentiation }}
{{Clusters of differentiation }}
{{WikiDoc Sources}}
{{Coagulation}}
{{Integrins}}
 
[[Category:Integrins]]
 
 
{{gene-17-stub}}

Latest revision as of 09:24, 30 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene.[1] CD61 is a cluster of differentiation found on thrombocytes.[2]

Structure and function

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface-mediated signaling.[3]

Role in endometriosis

Defectively expressed β3 integrin subunit has been correlated with presence of endometriosis, and has been suggested as a putative marker of this condition.[4]

Interactions

CD61 has been shown to interact with PTK2,[5][6] ITGB3BP,[7][8] TLN1[9][10] and CIB1.[11]

See also

References

  1. ↑ Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, Kaos FT, Schwartz E, Phillips D, Bennett JS, et al. (August 1988). "Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa". J Clin Invest. 81 (6): 1993–8. doi:10.1172/JCI113548. PMC 442653. PMID 2454952.
  2. ↑ Heemskerk, J. W. M.; Mattheij, N. J. A.; Cosemans, J. M. E. M. (2013). "Platelet-based coagulation: different populations, different functions". Journal of Thrombosis and Haemostasis. 11 (1): 2–16. doi:10.1111/jth.12045. ISSN 1538-7933.
  3. ↑ "Entrez Gene: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)".
  4. ↑ May, K. E.; Villar, J.; Kirtley, S.; Kennedy, S. H.; Becker, C. M. (2011). "Endometrial alterations in endometriosis: A systematic review of putative biomarkers". Human Reproduction Update. 17 (5): 637–653. doi:10.1093/humupd/dmr013. PMID 21672902.
  5. ↑ Eliceiri, Brian P; Puente Xose S; Hood John D; Stupack Dwayne G; Schlaepfer David D; Huang Xiaozhu Z; Sheppard Dean; Cheresh David A (April 2002). "Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling". J. Cell Biol. United States. 157 (1): 149–60. doi:10.1083/jcb.200109079. ISSN 0021-9525. PMC 2173263. PMID 11927607.
  6. ↑ Chung, J; Gao A G; Frazier W A (June 1997). "Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3". J. Biol. Chem. UNITED STATES. 272 (23): 14740–6. doi:10.1074/jbc.272.23.14740. ISSN 0021-9258. PMID 9169439.
  7. ↑ Fujimoto, Tetsuro-Takahiro; Katsutani Shinya; Shimomura Takeshi; Fujimura Kingo (January 2002). "Novel alternatively spliced form of beta(3)-endonexin". Thromb. Res. United States. 105 (1): 63–70. doi:10.1016/S0049-3848(01)00405-4. ISSN 0049-3848. PMID 11864709.
  8. ↑ Shattil, S J; O'Toole T; Eigenthaler M; Thon V; Williams M; Babior B M; Ginsberg M H (November 1995). "Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit". J. Cell Biol. UNITED STATES. 131 (3): 807–16. doi:10.1083/jcb.131.3.807. ISSN 0021-9525. PMC 2120613. PMID 7593198.
  9. ↑ Patil, S; Jedsadayanmata A; Wencel-Drake J D; Wang W; Knezevic I; Lam S C (October 1999). "Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding functions. The talin n-terminal head domain interacts with the membrane-proximal region of the beta(3) cytoplasmic tail". J. Biol. Chem. UNITED STATES. 274 (40): 28575–83. doi:10.1074/jbc.274.40.28575. ISSN 0021-9258. PMID 10497223.
  10. ↑ Calderwood, David A; Yan Boxu; de Pereda Jose M; Alvarez Begoña García; Fujioka Yosuke; Liddington Robert C; Ginsberg Mark H (June 2002). "The phosphotyrosine binding-like domain of talin activates integrins". J. Biol. Chem. United States. 277 (24): 21749–58. doi:10.1074/jbc.M111996200. ISSN 0021-9258. PMID 11932255.
  11. ↑ Naik, U P; Patel P M; Parise L V (February 1997). "Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain". J. Biol. Chem. UNITED STATES. 272 (8): 4651–4. doi:10.1074/jbc.272.8.4651. ISSN 0021-9258. PMID 9030514.

Further reading

External links


Retrieved from "https://www.wikidoc.org/index.php?title=CD61&oldid=1417771"