F11 receptor

Jump to navigation Jump to search

{{#invoke:Infobox_gene|getTemplateData}} Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene.<ref name="pmid10395639">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref name="pmid7646439">{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref><ref name="entrez">{{#invoke:citation/CS1|citation |CitationClass=web }}</ref> It has also been designated as CD321 (cluster of differentiation 321).

Function[edit]

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple transcript variants encoding two different isoforms have been found for this gene.<ref name="entrez"/>

Interactions[edit]

F11 receptor has been shown to interact with MLLT4,<ref name=pmid10856295>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref> CASK<ref name=pmid10856295/><ref name=pmid11120739>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref> and Tight junction protein 1.<ref name=pmid10856295/><ref name=pmid12953056>{{#invoke:Citation/CS1|citation |CitationClass=journal }}</ref>

References[edit]

<references group="" responsive="1"></references>

{{#invoke:Check for unknown parameters|check|unknown=|preview=Page using Template:Reflist with unknown parameter "_VALUE_"|ignoreblank=y| 1 | colwidth | group | liststyle | refs }}

Further reading[edit]

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

  • {{#invoke:Citation/CS1|citation

|CitationClass=journal }}

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

{{#invoke:Navbox|navbox}} {{#invoke:Navbox|navbox}}


{{#invoke:Asbox|main}}