CD52

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CD52 molecule
Identifiers
SymbolCD52
Alt. symbolsCDW52
Entrez1043
HUGO1804
OMIM114280
RefSeqNM_001803
UniProtP31358
Other data
LocusChr. 1 p36

CD52 is a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It is a glycosylphosphatidylinositol (GPI)--anchored antigen expressed on the all lymphocytes as well as within the male genital tract.

It is the protein targeted by Alemtuzumab.

It is associated with certain types of lymphoma.[1]

References

  1. Piccaluga PP, Agostinelli C, Righi S, Zinzani PL, Pileri SA (2007). "Expression of CD52 in peripheral T-cell lymphoma". Haematologica. 92 (4): 566–7. PMID 17488672.

External links

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