CD29
Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||||
Symbols | ITGB1 ; CD29; FNRB; GPIIA; MDF2; MSK12; VLAB | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 22999 | ||||||||||
| |||||||||||
RNA expression pattern | |||||||||||
More reference expression data | |||||||||||
Orthologs | |||||||||||
Template:GNF Ortholog box | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | n/a | n/a | |||||||||
Ensembl | n/a | n/a | |||||||||
UniProt | n/a | n/a | |||||||||
RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), also known as ITGB1 or CD29, is a human gene. CD29 is an integrin unit associated with very late antigen receptors.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit. Six alternatively spliced variants have been found for this gene which encode five proteins with alternate carboxy termini.[1]
References
Further reading
- Evans JP (2001). "Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization". Bioessays. 23 (7): 628–39. doi:10.1002/bies.1088. PMID 11462216.
- Armulik A (2002). "Splice variants of human beta 1 integrins: origin, biosynthesis and functions". Front. Biosci. 7: d219–27. PMID 11779688.
- Brakebusch C, Fässler R (2006). "beta 1 integrin function in vivo: adhesion, migration and more". Cancer Metastasis Rev. 24 (3): 403–11. doi:10.1007/s10555-005-5132-5. PMID 16258728.
External links
- CD29+Antigen at the US National Library of Medicine Medical Subject Headings (MeSH)
This immunology article is a stub. You can help Wikipedia by expanding it. |