Gamma-glutamyltransferase 1: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Bot: HTTP→HTTPS)
 
(removed no longer needed PBB controls and templates consistent citation formatting; wikify)
Line 1: Line 1:
{{Infobox_gene}}
{{Infobox_gene}}
'''Gamma-glutamyltransferase 1''' ('''GGT1'''), also known as '''CD224''' (Cluster of Differentiation 224), is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GGT1 gamma-glutamyltransferase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2678| accessdate = }}</ref>
'''Gamma-glutamyltransferase 1''' ('''GGT1'''), also known as '''CD224''' (Cluster of Differentiation 224), is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GGT1 gamma-glutamyltransferase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2678| access-date = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{PBB_Summary
| section_title =  
| summary_text = Human [[gamma-glutamyltransferase]] catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. This heteroduplex enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized. This gene encodes several transcript variants; studies suggest that many transcripts of this gene family may be non-functional or represent pseudogenes. The functional transcripts which have been fully characterized have been grouped and classified as type I gamma-glutamyltransferase. Complex splicing events may take place in a tissue-specific manner, resulting in marked dissimilarity in the 5' UTRs. Several 5' UTR transcript variants of the type I gene have been identified in different tissues and cancer cells.<ref name="entrez" />
}}


==See also==
Human [[gamma-glutamyltransferase]] catalyzes the transfer of the glutamyl moiety of [[glutathione]] to a variety of amino acids and dipeptide acceptors. This heteroduplex enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized. This gene encodes several transcript variants; studies suggest that many transcripts of this gene family may be non-functional or represent [[pseudogene]]s. The functional transcripts which have been fully characterized have been grouped and classified as type I gamma-glutamyltransferase. Complex splicing events may take place in a tissue-specific manner, resulting in marked dissimilarity in the [[5' UTR]]s. Several 5' UTR transcript variants of the type I gene have been identified in different tissues and cancer cells.<ref name="entrez" />
 
== See also ==
* [[Cluster of differentiation]]
* [[Cluster of differentiation]]


==References==
== References ==
{{reflist}}
{{reflist}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin|2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Chikhi N, Holic N, Guellaen G, Laperche Y | title = Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species | journal = Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology | volume = 122 | issue = 4 | pages = 367–80 | date = April 1999 | pmid = 10392451 | doi = 10.1016/S0305-0491(99)00013-9 }}
| citations =
* {{cite journal | vauthors = Indirani N, Hill PG | title = Partial purification and some properties of gamma-glutamyl transpeptidase from human bile | journal = Biochimica et Biophysica Acta | volume = 483 | issue = 1 | pages = 57–62 | date = July 1977 | pmid = 18198 | doi = 10.1016/0005-2744(77)90007-9 }}
*{{cite journal |vauthors=Chikhi N, Holic N, Guellaen G, Laperche Y |title=Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species |journal=Comp. Biochem. Physiol. B, Biochem. Mol. Biol. |volume=122 |issue= 4 |pages= 367–80 |year= 1999 |pmid= 10392451 |doi=10.1016/S0305-0491(99)00013-9 }}
* {{cite journal | vauthors = Tate SS, Ross ME | title = Human kidney gamma-glutamyl transpeptidase. Catalytic properties, subunit structure, and localization of the gamma-glutamyl binding site on the light subunit | journal = The Journal of Biological Chemistry | volume = 252 | issue = 17 | pages = 6042–5 | date = September 1977 | pmid = 19463 | doi =  }}
*{{cite journal |vauthors=Indirani N, Hill PG |title=Partial purification and some properties of gamma-glutamyl transpeptidase from human bile |journal=Biochim. Biophys. Acta |volume=483 |issue= 1 |pages= 57–62 |year= 1977 |pmid= 18198 |doi= 10.1016/0005-2744(77)90007-9}}
* {{cite journal | vauthors = Welbourne TC | title = Cytoplasmic gamma-glutamyltransferase: isolation, product formation and physiological role | journal = Current Problems in Clinical Biochemistry | volume = 8 | issue =  | pages = 201–15 | year = 1978 | pmid = 28899 | doi =  }}
*{{cite journal |vauthors=Tate SS, Ross ME |title=Human kidney gamma-glutamyl transpeptidase. Catalytic properties, subunit structure, and localization of the gamma-glutamyl binding site on the light subunit |journal=J. Biol. Chem. |volume=252 |issue= 17 |pages= 6042–5 |year= 1977 |pmid= 19463 |doi=  }}
* {{cite journal | vauthors = Courtay C, Oster T, Michelet F, Visvikis A, Diederich M, Wellman M, Siest G | title = Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues | journal = Biochemical Pharmacology | volume = 43 | issue = 12 | pages = 2527–33 | date = June 1992 | pmid = 1378736 | doi = 10.1016/0006-2952(92)90140-E }}
*{{cite journal | author=Welbourne TC |title=Cytoplasmic gamma-glutamyltransferase: isolation, product formation and physiological role |journal=Current problems in clinical biochemistry |volume=8 |issue=  |pages= 201–15 |year= 1978 |pmid= 28899 |doi=  }}
* {{cite journal | vauthors = Pawlak A, Cohen EH, Octave JN, Schweickhardt R, Wu SJ, Bulle F, Chikhi N, Baik JH, Siegrist S, Guellaën G | title = An alternatively processed mRNA specific for gamma-glutamyl transpeptidase in human tissues | journal = The Journal of Biological Chemistry | volume = 265 | issue = 6 | pages = 3256–62 | date = February 1990 | pmid = 1968061 | doi =  }}
*{{cite journal | author=Courtay C |title=Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues |journal=Biochem. Pharmacol. |volume=43 |issue= 12 |pages= 2527–33 |year= 1992 |pmid= 1378736 |doi=10.1016/0006-2952(92)90140-E |name-list-format=vanc| author2=Oster T  | author3=Michelet F  | display-authors=3  | last4=Visvikis  | first4=A  | last5=Diederich  | first5=M  | last6=Wellman  | first6=M  | last7=Siest  | first7=G }}
* {{cite journal | vauthors = Pitot HC, Goodspeed D, Dunn T, Hendrich S, Maronpot RR, Moran S | title = Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis | journal = Toxicology and Applied Pharmacology | volume = 97 | issue = 1 | pages = 23–34 | date = January 1989 | pmid = 2563599 | doi = 10.1016/0041-008X(89)90052-5 }}
*{{cite journal | author=Pawlak A |title=An alternatively processed mRNA specific for gamma-glutamyl transpeptidase in human tissues |journal=J. Biol. Chem. |volume=265 |issue= 6 |pages= 3256–62 |year= 1990 |pmid= 1968061 |doi= |name-list-format=vanc| author2=Cohen EH  | author3=Octave JN  | display-authors=3  | last4=Schweickhardt  | first4=R  | last5=Wu  | first5=SJ  | last6=Bulle  | first6=F  | last7=Chikhi  | first7=N  | last8=Baik  | first8=JH  | last9=Siegrist  | first9=S  }}
* {{cite journal | vauthors = Goodspeed DC, Dunn TJ, Miller CD, Pitot HC | title = Human gamma-glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat | journal = Gene | volume = 76 | issue = 1 | pages = 1–9 | date = March 1989 | pmid = 2568315 | doi = 10.1016/0378-1119(89)90002-4 }}
*{{cite journal | author=Pitot HC |title=Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis |journal=Toxicol. Appl. Pharmacol. |volume=97 |issue= 1 |pages= 23–34 |year= 1989 |pmid= 2563599 |doi=10.1016/0041-008X(89)90052-5  |name-list-format=vanc| author2=Goodspeed D  | author3=Dunn T | display-authors=3  | last4=Hendrich  | first4=Suzanne  | last5=Maronpot  | first5=Robert R.  | last6=Moran  | first6=Susan  }}
* {{cite journal | vauthors = Pawlak A, Wu SJ, Bulle F, Suzuki A, Chikhi N, Ferry N, Baik JH, Siegrist S, Guellaën G | title = Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney | journal = Biochemical and Biophysical Research Communications | volume = 164 | issue = 2 | pages = 912–8 | date = October 1989 | pmid = 2573352 | doi = 10.1016/0006-291X(89)91545-3 }}
*{{cite journal |vauthors=Goodspeed DC, Dunn TJ, Miller CD, Pitot HC |title=Human gamma-glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat |journal=Gene |volume=76 |issue= 1 |pages= 1–9 |year= 1989 |pmid= 2568315 |doi=10.1016/0378-1119(89)90002-4  }}
* {{cite journal | vauthors = Laperche Y, Bulle F, Aissani T, Chobert MN, Aggerbeck M, Hanoune J, Guellaën G | title = Molecular cloning and nucleotide sequence of rat kidney gamma-glutamyl transpeptidase cDNA | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 83 | issue = 4 | pages = 937–41 | date = February 1986 | pmid = 2869484 | pmc = 322985 | doi = 10.1073/pnas.83.4.937 }}
*{{cite journal | author=Pawlak A |title=Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney |journal=Biochem. Biophys. Res. Commun. |volume=164 |issue= 2 |pages= 912–8 |year= 1989 |pmid= 2573352 |doi=10.1016/0006-291X(89)91545-3  |name-list-format=vanc| author2=Wu SJ  | author3=Bulle F  | display-authors=3  | last4=Suzuki  | first4=Atsuo  | last5=Chikhi  | first5=Naima  | last6=Ferry  | first6=Nicolas  | last7=Baik  | first7=Ja-Hyun  | last8=Siegrist  | first8=Sylvie  | last9=Guellaën  | first9=Georges  }}
* {{cite journal | vauthors = Bulle F, Mattei MG, Siegrist S, Pawlak A, Passage E, Chobert MN, Laperche Y, Guellaën G | title = Assignment of the human gamma-glutamyl transferase gene to the long arm of chromosome 22 | journal = Human Genetics | volume = 76 | issue = 3 | pages = 283–6 | date = July 1987 | pmid = 2885259 | doi = 10.1007/BF00283624 }}
*{{cite journal  | author=Laperche Y |title=Molecular cloning and nucleotide sequence of rat kidney gamma-glutamyl transpeptidase cDNA |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 4 |pages= 937–41 |year= 1986 |pmid= 2869484 |doi=10.1073/pnas.83.4.937  | pmc=322985  |name-list-format=vanc| author2=Bulle F  | author3=Aissani T  | display-authors=3  | last4=Chobert  | first4=MN  | last5=Aggerbeck  | first5=M  | last6=Hanoune  | first6=J  | last7=Guellaën  | first7=G  }}
* {{cite journal | vauthors = Tate SS, Khadse V, Wellner D | title = Renal gamma-glutamyl transpeptidases: structural and immunological studies | journal = Archives of Biochemistry and Biophysics | volume = 262 | issue = 2 | pages = 397–408 | date = May 1988 | pmid = 2896486 | doi = 10.1016/0003-9861(88)90390-6 }}
*{{cite journal | author=Bulle F |title=Assignment of the human gamma-glutamyl transferase gene to the long arm of chromosome 22 |journal=Hum. Genet. |volume=76 |issue= 3 |pages= 283–6 |year= 1987 |pmid= 2885259 |doi=10.1007/BF00283624  |name-list-format=vanc| author2=Mattei MG  | author3=Siegrist S  | display-authors=3  | last4=Pawlak  | first4=A.  | last5=Passage  | first5=E.  | last6=Chobert  | first6=M.N. | last7=Laperche  | first7=Y. | last8=Guella�n  | first8=G. }}
* {{cite journal | vauthors = Tate SS, Galbraith RA | title = In vitro translation and processing of human hepatoma cell (Hep G2) gamma-glutamyl transpeptidase | journal = Biochemical and Biophysical Research Communications | volume = 154 | issue = 3 | pages = 1167–73 | date = August 1988 | pmid = 2900635 | doi = 10.1016/0006-291X(88)90263-X }}
*{{cite journal |vauthors=Tate SS, Khadse V, Wellner D |title=Renal gamma-glutamyl transpeptidases: structural and immunological studies |journal=Arch. Biochem. Biophys. |volume=262 |issue= 2 |pages= 397–408 |year= 1988 |pmid= 2896486 |doi=10.1016/0003-9861(88)90390-6 }}
* {{cite journal | vauthors = Rajpert-De Meyts E, Heisterkamp N, Groffen J | title = Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 85 | issue = 23 | pages = 8840–4 | date = December 1988 | pmid = 2904146 | pmc = 282602 | doi = 10.1073/pnas.85.23.8840 }}
*{{cite journal |vauthors=Tate SS, Galbraith RA |title=In vitro translation and processing of human hepatoma cell (Hep G2) gamma-glutamyl transpeptidase |journal=Biochem. Biophys. Res. Commun. |volume=154 |issue= 3 |pages= 1167–73 |year= 1988 |pmid= 2900635 |doi=10.1016/0006-291X(88)90263-X  }}
* {{cite journal | vauthors = Sakamuro D, Yamazoe M, Matsuda Y, Kangawa K, Taniguchi N, Matsuo H, Yoshikawa H, Ogasawara N | title = The primary structure of human gamma-glutamyl transpeptidase | journal = Gene | volume = 73 | issue = 1 | pages = 1–9 | date = December 1988 | pmid = 2907498 | doi = 10.1016/0378-1119(88)90307-1 }}
*{{cite journal  |vauthors=Rajpert-De Meyts E, Heisterkamp N, Groffen J |title=Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 23 |pages= 8840–4 |year= 1988 |pmid= 2904146 |doi=10.1073/pnas.85.23.8840  | pmc=282602  }}
* {{cite journal | vauthors = Ikeda Y, Fujii J, Anderson ME, Taniguchi N, Meister A | title = Involvement of Ser-451 and Ser-452 in the catalysis of human gamma-glutamyl transpeptidase | journal = The Journal of Biological Chemistry | volume = 270 | issue = 38 | pages = 22223–8 | date = September 1995 | pmid = 7673200 | doi = 10.1074/jbc.270.38.22223 }}
*{{cite journal  | author=Sakamuro D |title=The primary structure of human gamma-glutamyl transpeptidase |journal=Gene |volume=73 |issue= 1 |pages= 1–9 |year= 1989 |pmid= 2907498 |doi=10.1016/0378-1119(88)90307-1  |name-list-format=vanc| author2=Yamazoe M  | author3=Matsuda Y  | display-authors=3  | last4=Kenji  | first4=Kangawa  | last5=Naoyuki  | first5=Taniguchi  | last6=Hisayuki  | first6=Matsuo  | last7=Hiroshi  | first7=Yoshikawa  | last8=Naotake  | first8=Ogasawara  }}
* {{cite journal | vauthors = Wetmore LA, Gerard C, Drazen JM | title = Human lung expresses unique gamma-glutamyl transpeptidase transcripts | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 90 | issue = 16 | pages = 7461–5 | date = August 1993 | pmid = 7689219 | pmc = 47161 | doi = 10.1073/pnas.90.16.7461 }}
*{{cite journal  | author=Ikeda Y |title=Involvement of Ser-451 and Ser-452 in the catalysis of human gamma-glutamyl transpeptidase |journal=J. Biol. Chem. |volume=270 |issue= 38 |pages= 22223–8 |year= 1995 |pmid= 7673200 |doi=10.1074/jbc.270.38.22223  |name-list-format=vanc| author2=Fujii J  | author3=Anderson ME  | display-authors=3  | last4=Taniguchi  | first4=N  | last5=Meister  | first5=A  }}
* {{cite journal | vauthors = Ikeda Y, Fujii J, Taniguchi N, Meister A | title = Human gamma-glutamyl transpeptidase mutants involving conserved aspartate residues and the unique cysteine residue of the light subunit | journal = The Journal of Biological Chemistry | volume = 270 | issue = 21 | pages = 12471–5 | date = May 1995 | pmid = 7759490 | doi = 10.1074/jbc.270.21.12471 }}
*{{cite journal  |vauthors=Wetmore LA, Gerard C, Drazen JM |title=Human lung expresses unique gamma-glutamyl transpeptidase transcripts |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 16 |pages= 7461–5 |year= 1993 |pmid= 7689219 |doi=10.1073/pnas.90.16.7461  | pmc=47161  }}
* {{cite journal | vauthors = Courtay C, Heisterkamp N, Siest G, Groffen J | title = Expression of multiple gamma-glutamyltransferase genes in man | journal = The Biochemical Journal | volume = 297 | issue = Pt 3 | pages = 503–8 | date = February 1994 | pmid = 7906515 | pmc = 1137862 | doi =  }}
*{{cite journal  |vauthors=Ikeda Y, Fujii J, Taniguchi N, Meister A |title=Human gamma-glutamyl transpeptidase mutants involving conserved aspartate residues and the unique cysteine residue of the light subunit |journal=J. Biol. Chem. |volume=270 |issue= 21 |pages= 12471–5 |year= 1995 |pmid= 7759490 |doi=10.1074/jbc.270.21.12471  }}
* {{cite journal | vauthors = Ikeda Y, Fujii J, Taniguchi N | title = Significance of Arg-107 and Glu-108 in the catalytic mechanism of human gamma-glutamyl transpeptidase. Identification by site-directed mutagenesis | journal = The Journal of Biological Chemistry | volume = 268 | issue = 6 | pages = 3980–5 | date = February 1993 | pmid = 8095045 | doi =  }}
*{{cite journal  |vauthors=Courtay C, Heisterkamp N, Siest G, Groffen J |title=Expression of multiple gamma-glutamyltransferase genes in man |journal=Biochem. J. |volume=297 ( Pt 3) |issue=  Pt 3|pages= 503–8 |year= 1994 |pmid= 7906515 |doi=  | pmc=1137862  }}
*{{cite journal  |vauthors=Ikeda Y, Fujii J, Taniguchi N |title=Significance of Arg-107 and Glu-108 in the catalytic mechanism of human gamma-glutamyl transpeptidase. Identification by site-directed mutagenesis |journal=J. Biol. Chem. |volume=268 |issue= 6 |pages= 3980–5 |year= 1993 |pmid= 8095045 |doi=  }}
}}
{{refend}}
{{refend}}


==External links==
== External links ==
* {{MeshName| GGT1 +protein,+human}}
* {{MeshName| GGT1 +protein,+human}}


{{NLM content}}
{{NLM content}}
{{Clusters of differentiation}}
{{Clusters of differentiation}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


[[Category:Clusters of differentiation]]
[[Category:Clusters of differentiation]]


{{membrane-protein-stub}}
{{membrane-protein-stub}}

Revision as of 06:29, 19 September 2018

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Gamma-glutamyltransferase 1 (GGT1), also known as CD224 (Cluster of Differentiation 224), is a human gene.[1]

Function

Human gamma-glutamyltransferase catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. This heteroduplex enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein, and is present in tissues involved in absorption and secretion. This enzyme is a member of the gamma-glutamyltransferase protein family, of which many members have not yet been fully characterized. This gene encodes several transcript variants; studies suggest that many transcripts of this gene family may be non-functional or represent pseudogenes. The functional transcripts which have been fully characterized have been grouped and classified as type I gamma-glutamyltransferase. Complex splicing events may take place in a tissue-specific manner, resulting in marked dissimilarity in the 5' UTRs. Several 5' UTR transcript variants of the type I gene have been identified in different tissues and cancer cells.[1]

See also

References

  1. ↑ 1.0 1.1 "Entrez Gene: GGT1 gamma-glutamyltransferase 1".

Further reading

  • Chikhi N, Holic N, Guellaen G, Laperche Y (April 1999). "Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species". Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 122 (4): 367–80. doi:10.1016/S0305-0491(99)00013-9. PMID 10392451.
  • Indirani N, Hill PG (July 1977). "Partial purification and some properties of gamma-glutamyl transpeptidase from human bile". Biochimica et Biophysica Acta. 483 (1): 57–62. doi:10.1016/0005-2744(77)90007-9. PMID 18198.
  • Tate SS, Ross ME (September 1977). "Human kidney gamma-glutamyl transpeptidase. Catalytic properties, subunit structure, and localization of the gamma-glutamyl binding site on the light subunit". The Journal of Biological Chemistry. 252 (17): 6042–5. PMID 19463.
  • Welbourne TC (1978). "Cytoplasmic gamma-glutamyltransferase: isolation, product formation and physiological role". Current Problems in Clinical Biochemistry. 8: 201–15. PMID 28899.
  • Courtay C, Oster T, Michelet F, Visvikis A, Diederich M, Wellman M, Siest G (June 1992). "Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. Evidence for a ubiquitous gamma-glutamyltransferase polypeptide in human tissues". Biochemical Pharmacology. 43 (12): 2527–33. doi:10.1016/0006-2952(92)90140-E. PMID 1378736.
  • Pawlak A, Cohen EH, Octave JN, Schweickhardt R, Wu SJ, Bulle F, Chikhi N, Baik JH, Siegrist S, Guellaën G (February 1990). "An alternatively processed mRNA specific for gamma-glutamyl transpeptidase in human tissues". The Journal of Biological Chemistry. 265 (6): 3256–62. PMID 1968061.
  • Pitot HC, Goodspeed D, Dunn T, Hendrich S, Maronpot RR, Moran S (January 1989). "Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis". Toxicology and Applied Pharmacology. 97 (1): 23–34. doi:10.1016/0041-008X(89)90052-5. PMID 2563599.
  • Goodspeed DC, Dunn TJ, Miller CD, Pitot HC (March 1989). "Human gamma-glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat". Gene. 76 (1): 1–9. doi:10.1016/0378-1119(89)90002-4. PMID 2568315.
  • Pawlak A, Wu SJ, Bulle F, Suzuki A, Chikhi N, Ferry N, Baik JH, Siegrist S, Guellaën G (October 1989). "Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney". Biochemical and Biophysical Research Communications. 164 (2): 912–8. doi:10.1016/0006-291X(89)91545-3. PMID 2573352.
  • Laperche Y, Bulle F, Aissani T, Chobert MN, Aggerbeck M, Hanoune J, Guellaën G (February 1986). "Molecular cloning and nucleotide sequence of rat kidney gamma-glutamyl transpeptidase cDNA". Proceedings of the National Academy of Sciences of the United States of America. 83 (4): 937–41. doi:10.1073/pnas.83.4.937. PMC 322985. PMID 2869484.
  • Bulle F, Mattei MG, Siegrist S, Pawlak A, Passage E, Chobert MN, Laperche Y, Guellaën G (July 1987). "Assignment of the human gamma-glutamyl transferase gene to the long arm of chromosome 22". Human Genetics. 76 (3): 283–6. doi:10.1007/BF00283624. PMID 2885259.
  • Tate SS, Khadse V, Wellner D (May 1988). "Renal gamma-glutamyl transpeptidases: structural and immunological studies". Archives of Biochemistry and Biophysics. 262 (2): 397–408. doi:10.1016/0003-9861(88)90390-6. PMID 2896486.
  • Tate SS, Galbraith RA (August 1988). "In vitro translation and processing of human hepatoma cell (Hep G2) gamma-glutamyl transpeptidase". Biochemical and Biophysical Research Communications. 154 (3): 1167–73. doi:10.1016/0006-291X(88)90263-X. PMID 2900635.
  • Rajpert-De Meyts E, Heisterkamp N, Groffen J (December 1988). "Cloning and nucleotide sequence of human gamma-glutamyl transpeptidase". Proceedings of the National Academy of Sciences of the United States of America. 85 (23): 8840–4. doi:10.1073/pnas.85.23.8840. PMC 282602. PMID 2904146.
  • Sakamuro D, Yamazoe M, Matsuda Y, Kangawa K, Taniguchi N, Matsuo H, Yoshikawa H, Ogasawara N (December 1988). "The primary structure of human gamma-glutamyl transpeptidase". Gene. 73 (1): 1–9. doi:10.1016/0378-1119(88)90307-1. PMID 2907498.
  • Ikeda Y, Fujii J, Anderson ME, Taniguchi N, Meister A (September 1995). "Involvement of Ser-451 and Ser-452 in the catalysis of human gamma-glutamyl transpeptidase". The Journal of Biological Chemistry. 270 (38): 22223–8. doi:10.1074/jbc.270.38.22223. PMID 7673200.
  • Wetmore LA, Gerard C, Drazen JM (August 1993). "Human lung expresses unique gamma-glutamyl transpeptidase transcripts". Proceedings of the National Academy of Sciences of the United States of America. 90 (16): 7461–5. doi:10.1073/pnas.90.16.7461. PMC 47161. PMID 7689219.
  • Ikeda Y, Fujii J, Taniguchi N, Meister A (May 1995). "Human gamma-glutamyl transpeptidase mutants involving conserved aspartate residues and the unique cysteine residue of the light subunit". The Journal of Biological Chemistry. 270 (21): 12471–5. doi:10.1074/jbc.270.21.12471. PMID 7759490.
  • Courtay C, Heisterkamp N, Siest G, Groffen J (February 1994). "Expression of multiple gamma-glutamyltransferase genes in man". The Biochemical Journal. 297 (Pt 3): 503–8. PMC 1137862. PMID 7906515.
  • Ikeda Y, Fujii J, Taniguchi N (February 1993). "Significance of Arg-107 and Glu-108 in the catalytic mechanism of human gamma-glutamyl transpeptidase. Identification by site-directed mutagenesis". The Journal of Biological Chemistry. 268 (6): 3980–5. PMID 8095045.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Retrieved from "https://www.wikidoc.org/index.php?title=Gamma-glutamyltransferase_1&oldid=1518976"