Tolfenamic acid

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Tolfenamic acid
Tolenamic acid Wiki Str.png
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
oral
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
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Chemical and physical data
FormulaC14H12ClNO2
Molar mass261.707 g/mol
3D model (JSmol)
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List of terms related to Tolfenamic acid

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tolfenamic acid (TA) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.

Other possible uses

A study concludes, "TA was found significantly better than placebo in the subjective evaluation of drug efficacy (p<0.001) and in reducing the reported hangover symptoms in general (p < 0.01). In the TA group, significantly lower symptom scores were obtained for headache (p<0.01), and for nausea, vomiting, irritation, tremor, thirst and dryness of mouth (all p < 0.05)."[1]

Commercial names

Commercial names for tolfenamic acid include Clotam Rapid, Migrex and Tufnil for use in humans and Tolfedine for veterinary use in cats and dogs. This drug should not be confused with Tolmetin.

References

  1. 1.0 1.1 Kim Vilbour Andersen, Sine Larsen, Børge Alhede, Niels Gelting and Ole Buchardt (1989). = P29890001443 "Characterization of two polymorphic forms of tolfenamic acid, N-(2-methyl-3-chlorophenyl)anthranilic acid: their crystal structures and relative stabilities" Check |url= value (help). J. Chem. Soc., Perkin Trans. 2 (10): 1443–1447. doi:10.1039/P29890001443.

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