Ferroportin

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solute carrier family 40 (iron-regulated transporter), member 1
Identifiers
Symbol SLC40A1
Alt. Symbols SLC11A3 FPN1
Entrez 30061
HUGO 10909
OMIM 604653
RefSeq NM_014585
UniProt Q9NP59
Other data
Locus Chr. 2 q32

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Ferroportin

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Ferroportin is a transmembrane protein that transports iron from the inside of a cell to the outside of it. It is found on the surface of cells that store or transport iron, including:

Recent research suggests that ferroportin is the key molecule regulated by hepcidin, the apparent "master regulator" of human iron metabolism.

Clinical significance

Ferroportin can be associated with African iron overload.

External links

de:Ferroportin
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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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