SLC9A6

Solute carrier family 9 (sodium/hydrogen exchanger), member 6
Identifiers
Symbol(s)	SLC9A6; KIAA0267; NHE6
External IDs	OMIM: 300231 MGI: 2443511 Homologene: 55971
Gene ontology Molecular Function: • antiporter activity • solute:hydrogen antiporter activity • sodium:hydrogen antiporter activity • sodium ion binding Cellular Component: • mitochondrion • endoplasmic reticulum membrane • microsome • membrane • integral to membrane Biological Process: • ion transport • sodium ion transport • regulation of pH
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	10479	236794
Ensembl	ENSG00000198689	ENSMUSG00000060681
Uniprot	Q92581	na
Refseq	NM_001042537 (mRNA) NP_001036002 (protein)	NM_172780 (mRNA) NP_766368 (protein)
Location	Chr X: 134.9 - 134.96 Mb	Chr X: 52.96 - 53.01 Mb
Pubmed search	[1]	[2]

Solute carrier family 9 (sodium/hydrogen exchanger), member 6, also known as SLC9A6, is a human gene.

See also

• MeSH SLC9A6+protein,+human

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Brett CL, Wei Y, Donowitz M, Rao R (2002). "Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria.". Am. J. Physiol., Cell Physiol. 282 (5): C1031-41. doi:10.1152/ajpcell.00420.2001. PMID 11940519.
• Cheng J, Moyer BD, Milewski M, et al. (2002). "A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression.". J. Biol. Chem. 277 (5): 3520-9. doi:10.1074/jbc.M110177200. PMID 11707463.
• Miyazaki E, Sakaguchi M, Wakabayashi S, et al. (2002). "NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell.". J. Biol. Chem. 276 (52): 49221-7. doi:10.1074/jbc.M106267200. PMID 11641397.
• Numata M, Orlowski J (2001). "Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network.". J. Biol. Chem. 276 (20): 17387-94. doi:10.1074/jbc.M101319200. PMID 11279194.
• Numata M, Petrecca K, Lake N, Orlowski J (1998). "Identification of a mitochondrial Na+/H+ exchanger.". J. Biol. Chem. 273 (12): 6951-9. PMID 9507001.
• Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321-9, 341-54. PMID 9039502.

Template:Membrane-protein-stub This article incorporates text from the United States National Library of Medicine, which is in the public domain.