SLC25A11

Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Identifiers
Symbol(s)	SLC25A11; OGC; SLC20A4
External IDs	OMIM: 604165 MGI: 1915113 Homologene: 2637
Gene ontology Molecular Function: • transporter activity • binding • oxoglutarate:malate antiporter activity Cellular Component: • mitochondrion • mitochondrial inner membrane • integral to plasma membrane • membrane Biological Process: • transport
RNA expression pattern
250px 250px More reference expression data
Orthologs
	Human	Mouse
Entrez	8402	67863
Ensembl	ENSG00000108528	ENSMUSG00000014606
Uniprot	Q02978	Q5SX46
Refseq	NM_003562 (mRNA) NP_003553 (protein)	NM_024211 (mRNA) NP_077173 (protein)
Location	Chr 17: 4.78 - 4.78 Mb	Chr 11: 70.46 - 70.46 Mb
Pubmed search	[1]	[2]

Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11, also known as SLC25A11, is a human gene.

See also

• Solute carrier family

Further reading

• Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier.". DNA Seq. 3 (2): 79-88. PMID 1457818.
• Bisaccia F, Zara V, Capobianco L, et al. (1996). "The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier.". Biochim. Biophys. Acta 1292 (2): 281-88. PMID 8597574.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107-13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Bisaccia F, Capobianco L, Mazzeo M, Palmieri F (1996). "The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224.". FEBS Lett. 392 (1): 54-8. PMID 8769314.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353-8. PMID 9110174.
• Palmisano A, Zara V, Hönlinger A, et al. (1998). "Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane.". Biochem. J. 333 ( Pt 1): 151-8. PMID 9639574.
• Piccininni S, Iacobazzi V, Lauria G, et al. (1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3.". Cytogenet. Cell Genet. 83 (3-4): 256-7. PMID 10072597.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Coll O, Colell A, García-Ruiz C, et al. (2003). "Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion.". Hepatology 38 (3): 692-702. doi:10.1053/jhep.2003.50351. PMID 12939596.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
• Kabe Y, Ohmori M, Shinouchi K, et al. (2006). "Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.". J. Biol. Chem. 281 (42): 31729-35. doi:10.1074/jbc.M604729200. PMID 16920706.