SLC2A6

Solute carrier family 2 (facilitated glucose transporter), member 6
Identifiers
Symbol(s)	SLC2A6; GLUT6; GLUT9; HSA011372
External IDs	OMIM: 606813 MGI: 2443286 Homologene: 69236
Gene ontology Molecular Function: • transporter activity • sugar:hydrogen ion symporter activity • glucose transmembrane transporter activity Cellular Component: • membrane • integral to membrane Biological Process: • carbohydrate transport
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	11182	227659
Ensembl	ENSG00000160326	ENSMUSG00000036067
Uniprot	Q9UGQ3	na
Refseq	NM_017585 (mRNA) NP_060055 (protein)	NM_172659 (mRNA) NP_766247 (protein)
Location	Chr 9: 135.33 - 135.33 Mb	Chr 2: 26.84 - 26.85 Mb
Pubmed search	[1]	[2]

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]

Overview

Solute carrier family 2 (facilitated glucose transporter), member 6, also known as SLC2A6, is a human gene.

Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that contain 12 transmembrane domains and a number of critical conserved residues.[supplied by OMIM]

See also

• Glucose transporter
• Solute carrier family

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
• Doege H, Bocianski A, Joost HG, Schürmann A (2001). "Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes.". Biochem. J. 350 Pt 3: 771-6. PMID 10970791.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Richardson S, Neama G, Phillips T, et al. (2003). "Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation.". Osteoarthr. Cartil. 11 (2): 92-101. PMID 12554125.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369-74. doi:10.1038/nature02465. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.