Adipocyte
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Overview
Adipocytes are the cells that primarily compose adipose tissue, specialized in storing energy as fat.
Description
There are two types of adipose tissue, white adipose tissue (WAT) and brown adipose tissue (BAT), which are also known as white fat and brown fat, respectively, and comprise two types of fat cells:
- White fat cells (also known as Unilocular Cells) contain a large lipid droplet surrounded by a ring of cytoplasm. The nucleus is flattened and located on the periphery.
The fat stored is in a semi-liquid state, and is composed primarily of triglycerides and cholesterol ester. White fat cells secrete resistin, adiponectin, and leptin.
- Brown fat cells (also known as Multilocular Cells) are polygonal in shape. Unlike white fat cells, these cells have considerable cytoplasm, with lipid droplets scattered throughout. The nucleus is round, and, although eccentrically located, it is not in the periphery of the cell. The brown color comes from the large quantity of mitochondria. Brown fat, also known as "baby fat," is used to generate heat.
Lineage
Although the lineage of adipocytes is still unclear, Preadipocytes are undifferentiated fibroblasts that can be stimulated to form adipocytes.
Mesenchymal stem cells can differentiate into adipocytes, connective tissue, muscle or bone.
Areolar connective tissue is composed of adipocytes.
External links
- Histology at BU 08201loa - "Connective Tissue: unilocular (white) adipocytes "
- Histology at BU 04901lob - "Connective Tissue: multilocular (brown) adipocytes"
Histology: connective tissue | |
|---|---|
| Classification | proper (loose/areolar, dense, adipose brown and white, reticular) embryonic (mucous, mesenchymal) specialized (cartilage, bone, blood) |
| Extracellular matrix | ground substance (tissue fluid) fibers (collagen, reticular fiber, elastic fibers) |
| Cells | resident (fibroblast, adipocyte, chondroblast, osteoblast), wandering cell |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 . cs:Tuková buňka de:Adipozytfr:Adipocyte it:Adipocita ja:脂肪細胞sk:Tuková bunka sr:Адипоцит fi:Rasvasolu sv:Fettcell
