African iron overload

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African iron overload, formerly known as Bantu siderosis, is an iron overload disorder first observed among people of African descent in Southern Africa. Originally, this was blamed on ungalvanised barrels used to store home-made beer, which led to increased oxidation and increased iron levels in the beer. Further investigation has shown that only some people drinking this sort of beer get an iron overload syndrome, and that a similar syndrome occurred in people of African descent who have had no contact with this kind of beer (e.g., African Americans). This led investigators to the discovery of a gene polymorphism in the gene for ferroportin, which predisposes some people of African descent to iron overload.

References

• Gordeuk VR, et al. Iron overload in Africans and African-Americans and a common mutation in the SCL40A1 (ferroportin 1) gene. Blood Cells Mol Dis. 2003 Nov-Dec;31(3):299-304. [3]
• Online 'Mendelian Inheritance in Man' (OMIM) 601195

v • d • e WikiDoc Research Resources for African iron overload
Articles on African iron overload	Most recent articles on African iron overload • Most cited articles on African iron overload • Review articles on African iron overload • Articles on African iron overload in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on African iron overload	Powerpoint slides on African iron overload • Images of African iron overload • Photos of African iron overload • Podcasts & MP3s on African iron overload • Videos on African iron overload
Evidence Based Medicine Regarding African iron overload	Cochrane Collaboration on African iron overload • Bandolier on African iron overload • TRIP on African iron overload
Cost Effectiveness of African iron overload	Cost Effectiveness of African iron overload
Clinical Trials Involving African iron overload	Ongoing Trials on African iron overload at Clinical Trials.gov • Trial results on African iron overload • Clinical Trials on African iron overload at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding African iron overload	US National Guidelines Clearinghouse on African iron overload • NICE Guidance on African iron overload • NHS PRODIGY Guidance • FDA on African iron overload • CDC on African iron overload
Textbook Information on African iron overload	Books and Textbook Information on African iron overload
Pharmacology Resources on African iron overload	Dosing of African iron overload • Drug interactions with African iron overload • Side effects of African iron overload • Allergic reactions to African iron overload • Overdose information on African iron overload • Carcinogenicity information on African iron overload • African iron overload in pregnancy • Pharmacokinetics of African iron overload •
Genetics, Pharmacogenomics, and Proteinomics of African iron overload	Genetics of African iron overload • Pharmacogenomics of African iron overload • Proteomics of African iron overload
Newstories on African iron overload	African iron overload in the news • Be alerted to news on African iron overload • News trends on African iron overload
Commentary on African iron overload	Blogs on African iron overload
Patient Resources on African iron overload	Patient resources on African iron overload • Discussion groups on African iron overload • Patient Handouts on African iron overload • Directions to Hospitals Treating African iron overload • Risk calculators and risk factors for African iron overload
Healthcare Provider Resources on African iron overload	Symptoms of African iron overload • Causes & Risk Factors for African iron overload • Diagnostic studies for African iron overload • Treatment of African iron overload
Continuing Medical Education (CME) Programs on African iron overload	CME Programs on African iron overload
International Resources on African iron overload	African iron overload en Espanol • African iron overload en Francais
Business Resources on African iron overload	African iron overload in the Marketplace • Patents on African iron overload
Informatics Resources on African iron overload	List of terms related to African iron overload

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .