SLC35A1

Solute carrier family 35 (CMP-sialic acid transporter), member A1
Identifiers
Symbol(s)	SLC35A1; CST; CMPST; hCST; inactive
External IDs	OMIM: 605634 MGI: 1345622 Homologene: 38181
Gene ontology Molecular Function: • nucleotide-sugar transmembrane transporter activity • sugar:hydrogen ion symporter activity • CMP-sialic acid transmembrane transporter activity Cellular Component: • Golgi membrane • Golgi apparatus • integral to plasma membrane • membrane • integral to membrane Biological Process: • carbohydrate metabolic process • protein modification process • carbohydrate transport • nucleotide-sugar transport • CMP-sialic acid transport
Orthologs
	Human	Mouse
Entrez	10559	24060
Refseq	NM_006416 (mRNA) NP_006407 (protein)	XM_001001620 (mRNA) XP_001001620 (protein)
Pubmed search	[1]	[2]

Solute carrier family 35 (CMP-sialic acid transporter), member A1, also known as SLC35A1, is a human gene.

See also

• Solute carrier family

Further reading

• Wahlberg JE (1976). "Sensitization and testing of guinea pigs with nickel sulfate.". Dermatologica 152 (6): 321-30. PMID 964426.
• Harvey BE, Thomas P (1993). "Inhibition of CMP-sialic acid transport in human liver and colorectal cancer cell lines by a sialic acid nucleoside conjugate (KI-8110).". Biochem. Biophys. Res. Commun. 190 (2): 571-5. doi:10.1006/bbrc.1993.1086. PMID 8427599.
• Lennon G, Auffray C, Polymeropoulos M, Soares MB (1996). "The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.". Genomics 33 (1): 151-2. doi:10.1006/geno.1996.0177. PMID 8617505.
• Ishida N, Miura N, Yoshioka S, Kawakita M (1997). "Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family.". J. Biochem. 120 (6): 1074-8. PMID 9010752.
• Ishida N, Ito M, Yoshioka S, et al. (1998). "Functional expression of human golgi CMP-sialic acid transporter in the Golgi complex of a transporter-deficient Chinese hamster ovary cell mutant.". J. Biochem. 124 (1): 171-8. PMID 9644260.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Aoki K, Ishida N, Kawakita M (2003). "Substrate recognition by nucleotide sugar transporters: further characterization of substrate recognition regions by analyses of UDP-galactose/CMP-sialic acid transporter chimeras and biochemical analysis of the substrate specificity of parental and chimeric transporters.". J. Biol. Chem. 278 (25): 22887-93. doi:10.1074/jbc.M302620200. PMID 12682060.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Martinez-Duncker I, Dupré T, Piller V, et al. (2005). "Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP-sialic acid transporter.". Blood 105 (7): 2671-6. doi:10.1182/blood-2004-09-3509. PMID 15576474.
• Misaki R, Fujiyama K, Seki T (2006). "Expression of human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter in tobacco suspension-cultured cell.". Biochem. Biophys. Res. Commun. 339 (4): 1184-9. doi:10.1016/j.bbrc.2005.11.130. PMID 16343442.
• Zhao W, Chen TL, Vertel BM, Colley KJ (2006). "The CMP-sialic acid transporter is localized in the medial-trans Golgi and possesses two specific endoplasmic reticulum export motifs in its carboxyl-terminal cytoplasmic tail.". J. Biol. Chem. 281 (41): 31106-18. doi:10.1074/jbc.M605564200. PMID 16923816.