OR52A1

Olfactory receptor, family 52, subfamily A, member 1
Identifiers
Symbol(s)	OR52A1; HPFH1OR
External IDs	Homologene: 85928
Gene ontology Molecular Function: • olfactory receptor activity Cellular Component: • integral to plasma membrane • membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	23538	na
Ensembl	ENSG00000182070	na
Uniprot	Q9UKL2	na
Refseq	NM_012375 (mRNA) NP_036507 (protein)	na (mRNA) na (protein)
Location	Chr 11: 5.13 - 5.16 Mb	na
Pubmed search	[1]	na

Olfactory receptor, family 52, subfamily A, member 1, also known as OR52A1, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Feingold EA, Penny LA, Nienhuis AW, Forget BG (1999). "An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells.". Genomics 61 (1): 15-23. doi:10.1006/geno.1999.5935. PMID 10512676.
• Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560-5. doi:10.1073/pnas.97.26.14560. PMID 11121057.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.

External links

• MeSH OR52A1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub