OR6B1

Olfactory receptor, family 6, subfamily B, member 1
Identifiers
Symbol(s)	OR6B1; OR7-3; OR7-9
External IDs	MGI: 3030283 Homologene: 17485
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	135946	259067
Ensembl	na	ENSMUSG00000049168
Refseq	NM_001005281 (mRNA) NP_001005281 (protein)	NM_147064 (mRNA) NP_667275 (protein)
Location	na	Chr 6: 42.77 - 42.77 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 6, subfamily B, member 1, also known as OR6B1, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.

External links

• MeSH OR6B1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub