OR7C2

Olfactory receptor, family 7, subfamily C, member 2
Identifiers
Symbol(s)	OR7C2; CIT-HSP-87M17; OR19-18; OR7C3
External IDs	MGI: 3031190 Homologene: 71958
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	26658	258305
Ensembl	ENSG00000127529	ENSMUSG00000051190
Uniprot	O60412	na
Refseq	NM_012377 (mRNA) NP_036509 (protein)	NM_146308 (mRNA) NP_666420 (protein)
Location	Chr 19: 14.91 - 14.91 Mb	Chr 10: 78.25 - 78.25 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 7, subfamily C, member 2, also known as OR7C2, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Taviaux S, Trask BJ, et al. (1998). "Distribution of olfactory receptor genes in the human genome.". Nat. Genet. 18 (3): 243-50. doi:10.1038/ng0398-243. PMID 9500546.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529-35. doi:10.1038/nature02399. PMID 15057824.

External links

• MeSH OR7C2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub