OR4C12

Olfactory receptor, family 4, subfamily C, member 12
Identifiers
Symbol(s)	OR4C12; OR11-259
External IDs	MGI: 3031089 Homologene: 82298
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	283093	258979
Ensembl	ENSG00000186419	ENSMUSG00000045148
Uniprot	Q96R67	na
Refseq	NM_001005270 (mRNA) NP_001005270 (protein)	NM_146977 (mRNA) NP_667188 (protein)
Location	Chr 11: 49.96 - 49.96 Mb	Chr 2: 89.62 - 89.62 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 4, subfamily C, member 12, also known as OR4C12, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.

External links

• MeSH OR4C12+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub