OR4E2

Olfactory receptor, family 4, subfamily E, member 2
Identifiers
Symbol(s)	OR4E2; OR14-42
External IDs	MGI: 3031343 Homologene: 41378
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	26686	57271
Ensembl	na	ENSMUSG00000035626
Refseq	NM_001001912 (mRNA) NP_001001912 (protein)	NM_020514 (mRNA) NP_065260 (protein)
Location	na	Chr 14: 51.37 - 51.37 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 4, subfamily E, member 2, also known as OR4E2, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Koop BF, Rowen L, Wang K, et al. (1994). "The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA.". Genomics 19 (3): 478-93. doi:10.1006/geno.1994.1097. PMID 8188290.
• Boysen C, Simon MI, Hood L (1997). "Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones.". Genome Res. 7 (4): 330-8. PMID 9110172.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.

External links

• MeSH OR4E2+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub