OR51E1

Olfactory receptor, family 51, subfamily E, member 1
Identifiers
Symbol(s)	OR51E1; D-GPCR; GPR164; MGC24137; OR51E1P; OR52A3P; POGR; PSGR2
External IDs	MGI: 3030392 Homologene: 17503
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	143503	259097
Ensembl	ENSG00000180785	ENSMUSG00000070423
Uniprot	Q8TCB6	na
Refseq	NM_152430 (mRNA) NP_689643 (protein)	NM_147093 (mRNA) NP_667304 (protein)
Location	Chr 11: 4.62 - 4.63 Mb	Chr 7: 102.58 - 102.59 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 51, subfamily E, member 1, also known as OR51E1, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Wang J, Weng J, Cai Y, et al. (2006). "The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase.". Prostate 66 (8): 847-57. doi:10.1002/pros.20389. PMID 16491480.
• Weng J, Wang J, Hu X, et al. (2007). "PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer.". Int. J. Cancer 118 (6): 1471-80. doi:10.1002/ijc.21527. PMID 16206286.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
• Weigle B, Fuessel S, Ebner R, et al. (2004). "D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate.". Biochem. Biophys. Res. Commun. 322 (1): 239-49. doi:10.1016/j.bbrc.2004.07.106. PMID 15313197.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
• Vanti WB, Nguyen T, Cheng R, et al. (2003). "Novel human G-protein-coupled receptors.". Biochem. Biophys. Res. Commun. 305 (1): 67-71. PMID 12732197.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.". Nature 377 (6547 Suppl): 3-174. PMID 7566098.

External links

• MeSH OR51E1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub