OR2A5

Olfactory receptor, family 2, subfamily A, member 5
Identifiers
Symbol(s)	OR2A5; OR2A11P; OR2A26; OR2A8; OR7-138; OR7-141
External IDs	MGI: 3030282 Homologene: 64846
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
Orthologs
	Human	Mouse
Entrez	393046	258270
Ensembl	na	ENSMUSG00000043119
Refseq	NM_012365 (mRNA) NP_036497 (protein)	NM_146273 (mRNA) NP_666385 (protein)
Location	na	Chr 6: 42.83 - 42.83 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 2, subfamily A, member 5, also known as OR2A5, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Taviaux S, Trask BJ, et al. (1998). "Distribution of olfactory receptor genes in the human genome.". Nat. Genet. 18 (3): 243-50. doi:10.1038/ng0398-243. PMID 9500546.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.

External links

• MeSH OR2A5+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub