OR10A3

Olfactory receptor, family 10, subfamily A, member 3
Identifiers
Symbol(s)	OR10A3; HSHTPCRX12; HTPCRX12
External IDs	MGI: 3030352 Homologene: 17186
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	26496	258303
Ensembl	ENSG00000170683	ENSMUSG00000046431
Uniprot	P58181	na
Refseq	NM_001003745 (mRNA) NP_001003745 (protein)	NM_146306 (mRNA) NP_666418 (protein)
Location	Chr 11: 7.92 - 7.92 Mb	Chr 7: 108.67 - 108.67 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 10, subfamily A, member 3, also known as OR10A3, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453-5. doi:10.1038/355453a0. PMID 1370859.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification.". Nature 440 (7083): 497-500. doi:10.1038/nature04632. PMID 16554811.

External links

• MeSH OR10A3+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub