OR6C4

Olfactory receptor, family 6, subfamily C, member 4
Identifiers
Symbol(s)	OR6C4; OR12-10
External IDs	MGI: 3030599 Homologene: 79371
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	341418	258315
Ensembl	ENSG00000179626	ENSMUSG00000056853
Uniprot	Q8NGE1	na
Refseq	NM_001005494 (mRNA) NP_001005494 (protein)	NM_146318 (mRNA) NP_666430 (protein)
Location	Chr 12: 54.23 - 54.23 Mb	Chr 10: 128.45 - 128.45 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 6, subfamily C, member 4, also known as OR6C4, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Lauzurica P, Bragado R, López D, et al. (1992). "Asymmetric selection of T cell antigen receptor alpha- and beta-chains in HLA-B27 alloreactivity.". J. Immunol. 148 (11): 3624-30. PMID 1316921.
• Youngblood K, Fruchter L, Ding G, et al. (1994). "Rheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutated.". J. Clin. Invest. 93 (2): 852-61. PMID 7509350.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.

External links

• MeSH OR6C4+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub