OR2C1

Olfactory receptor, family 2, subfamily C, member 1
Identifiers
Symbol(s)	OR2C1; MGC163200; MGC95444; OLFmf3; OR2C2P
External IDs	MGI: 106182 Homologene: 7459
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	4993	18312
Ensembl	ENSG00000168158	ENSMUSG00000059043
Uniprot	O95371	Q496W6
Refseq	NM_012368 (mRNA) NP_036500 (protein)	NM_008762 (mRNA) NP_032788 (protein)
Location	Chr 16: 3.35 - 3.35 Mb	Chr 16: 3.75 - 3.76 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 2, subfamily C, member 1, also known as OR2C1, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Centola M, Chen X, Sood R, et al. (1999). "Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3.". Genome Res. 8 (11): 1172-91. PMID 9847080.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.

External links

• MeSH OR2C1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub