OR10J1

Olfactory receptor, family 10, subfamily J, member 1
Identifiers
Symbol(s)	OR10J1; HGMP07J; HSHGMP07J; MGC138495; MGC138497
External IDs	MGI: 3030052 Homologene: 8218
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • integral to plasma membrane • membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • single fertilization • sensory perception of smell • response to stimulus
RNA expression pattern
250px More reference expression data
Orthologs
	Human	Mouse
Entrez	26476	258880
Ensembl	ENSG00000196184	ENSMUSG00000046643
Uniprot	P30954	na
Refseq	NM_012351 (mRNA) NP_036483 (protein)	NM_001001809 (mRNA) NP_001001809 (protein)
Location	Chr 1: 157.67 - 157.68 Mb	Chr 1: 175.04 - 175.04 Mb
Pubmed search	[1]	[2]

Olfactory receptor, family 10, subfamily J, member 1, also known as OR10J1, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells.". Nature 355 (6359): 453-5. doi:10.1038/355453a0. PMID 1370859.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.

External links

• MeSH OR10J1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub