OR2B3

Olfactory receptor, family 2, subfamily B, member 3
Identifiers
Symbol(s)	OR2B3; 6M1-1; 6M1-1*01; 6M1-1*02; OR6-14; OR6-4
External IDs	Homologene: 67858
Gene ontology Molecular Function: • receptor activity • olfactory receptor activity Cellular Component: • membrane • integral to membrane Biological Process: • signal transduction • G-protein coupled receptor protein signaling pathway • sensory perception of smell • response to stimulus
RNA expression pattern
250px 250px More reference expression data
Orthologs
	Human	Mouse
Entrez	442184	na
Ensembl	ENSG00000112453	na
Uniprot	O76000	na
Refseq	NM_001005226 (mRNA) NP_001005226 (protein)	na (mRNA) na (protein)
Location	Chr c6_COX: 29.2 - 29.2 Mb	na
Pubmed search	[1]	na

Olfactory receptor, family 2, subfamily B, member 3, also known as OR2B3, is a human gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.

External links

• MeSH OR2B3+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain. Template:Membrane-protein-stub