Neuropeptide Y receptor Y1

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VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene.[1][2]

Selective ligands

Agonists

Antagonists

Peptide
  • BVD-10 (selective NPY1 antagonist, CAS# 262418-00-8)
  • GR-231,118 (mixed NPY1 antagonist / NPY4 agonist, CAS# 158859-98-4)
Non-peptide
  • BIBO-3304 (CAS# 191868-14-1)
  • BIBP-3226 (CAS# 159013-54-4)
  • PD-160,170 (CAS# 181468-88-2)

Available Structures

  • 5ZBH (Neuropeptide Y1 bound to antagonist BMS-193835)[3]
  • 5ZBQ (Neuropeptide Y1 bound to antagonist UR-MK299)[3]

See also

References

  1. Herzog H, Baumgartner M, Vivero C, Selbie LA, Auer B, Shine J (March 1993). "Genomic organization, localization, and allelic differences in the gene for the human neuropeptide Y Y1 receptor". The Journal of Biological Chemistry. 268 (9): 6703–7. PMID 8095935.
  2. "Entrez Gene: NPY1R neuropeptide Y receptor Y1".
  3. 3.0 3.1 Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B (April 2018). "1 receptor". Nature. 556 (7702): 520–524. doi:10.1038/s41586-018-0046-x. PMC 5920736. PMID 29670288.

Further reading

External links


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