FZD5

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Frizzled-5 is a protein that in humans is encoded by the FZD5 gene.[1][2][3]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.[3]

See also

References

  1. Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Jun 1996). "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled". J Biol Chem. 271 (8): 4468–76. doi:10.1074/jbc.271.8.4468. PMID 8626800.
  2. Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region". Int J Oncol. 19 (1): 105–10. doi:10.3892/ijo.19.1.105. PMID 11408929.
  3. 3.0 3.1 "Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)".

External links

  • "Frizzled Receptors: FZD5". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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