The WikiDoc Living Textbook of Oncology
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
Click Here For A Complete Listing Of All Chapters In The Living Textbook Of Oncology In Alphabetical Order
Below you will find navigational boxes displaying major topics. Click on the right hand [ show ] button to display the entire contents of a navigational box.
Disease States
Nervous tissue tumors (ICD-O 9350-9589) | |
|---|---|
| Miscellaneous tumors (9350-9379) | Craniopharyngioma - Pinealoma |
| Glioma (9380-9489) | Gliomatosis cerebri - Oligoastrocytoma - Choroid plexus papilloma - Ependymoma - Astrocytoma (Pilocytic astrocytoma, Glioblastoma multiforme) - Dysembryoplastic neuroepithelial tumour - Oligodendroglioma - Medulloblastoma - Primitive neuroectodermal tumor |
| Neuroepitheliomatous (9490-9529) | Ganglioneuroma - Neuroblastoma - Atypical teratoid rhabdoid tumor - Retinoblastoma - Esthesioneuroblastoma |
| Meningiomas (9530-9539) | Meningioma |
| Nerve sheath tumor (9540-9579) | Neurofibroma (Neurofibrosarcoma, Neurofibromatosis) - Schwannoma - Neurinoma - Acoustic neuroma - Neuroma |
| see also brain tumors (though not all brain tumors are of nervous tissue) | |
Soft tissue tumors and sarcomas (ICD-O 8800-9349) | |
|---|---|
| Not otherwise specified (8800-8809) | Soft tissue sarcoma - Desmoplastic small round cell tumor |
| Fibromatous (8810-8839) | Fibroma/fibrosarcoma - Malignant fibrous histiocytoma - Dermatofibroma/dermatofibrosarcoma - Dermatofibrosarcoma protuberans |
| Myxomatous (8840-8849) | Myxoma - Ossifying fibromyxoid tumour |
| Lipomatous (8850-8889) | Lipoma/liposarcoma (Angiomyolipoma) |
| Myomatous (8890-8929) | Leiomyoma/leiomyosarcoma - Myoma - Rhabdomyoma/rhabdomyosarcoma - Sarcoma botryoides |
| Complex Mixed And Stromal (8930-8999) | Adenomyoma - Pleomorphic adenoma - Mixed Mullerian tumor - Mesoblastic nephroma - Wilms' tumor - Rhabdoid tumour - Clear cell sarcoma of the kidney - Hepatoblastoma - Carcinosarcoma |
| Fibroepithelial (9000-9039) | Brenner tumour - Fibroadenoma - Phyllodes tumor |
| Synovial-like (9040-9049) | Synovial sarcoma - Clear cell sarcoma, NOS |
| Mesothelial (9050-9059) | Mesothelioma - Adenomatoid tumor |
| Germ cell tumors (9060-9119) | germinomatous germ cell tumors: Dysgerminoma - Germinoma - Seminoma nongerminomatous germ cell tumors: Embryonal carcinoma - Endodermal sinus tumor / Yolk sac tumor - Teratoma/Fetus in fetu / Dermoid cyst/Struma ovarii - Gestational trophoblastic disease (Hydatidiform mole) - Choriocarcinoma - Polyembryoma - Gonadoblastoma |
| Vascular (9120-9179) | blood vessels: Hemangioma/hemangiosarcoma - Angioma/angiosarcoma - Blue rubber bleb nevus syndrome - Hemangioendothelioma - Kaposi's sarcoma - Hemangiopericytoma lymphatic vessels: Lymphangioma/lymphangiosarcoma - Lymphangioleiomyomatosis |
| Osseous and chondromatous (9180-9349) | Osteoma/osteosarcoma - Osteochondroma - Chondroma/enchondroma/chondrosarcoma - Chondroblastoma - Giant cell tumor of bone - Ewing's sarcoma - Chordoma
teeth/odontogenic: (Cementoblastoma, Cementoma, Odontoma, Adenomatoid odontogenic tumor, Ameloblastoma) Adamantinoma |
Pathology: Cancer, Tumors, Neoplasms, and oncology (C00-D48, 140-239) | |
|---|---|
| Benign tumors | Hyperplasia - Cyst - Pseudocyst - Hamartoma - Benign tumor |
| Malignant progression | Dysplasia - Carcinoma in situ - Cancer - Metastasis |
| Topography | lip, oral cavity and pharynx: Oral - Head/Neck - Nasopharyngeal
digestive system: tract (Esophagus, Stomach, Small intestine, Colon/rectum, Appendix, Anus) - glands (Liver, Bile duct, Gallbladder, Pancreas) respiratory system: Larynx - Lung bone, articular cartilage, skin, and connective tissue: Bone (Tailbone) - Skin - Blood urogenital: breast and female genital organs (Breast, Vagina, Cervix, Uterus, Endometrium, Ovaries) - male genital organs (Penis, Prostate, Testicles) - urinary organs (Kidney, Bladder) nervous system: Eye (Uvea) - Brain (Choroid plexus) endocrine system: Thyroid (Papillary, Follicular, Medullary, Anaplastic) - Adrenal tumor (Adrenocortical carcinoma, Pheochromocytoma) - Pituitary |
| Misc. | Tumor suppressor genes/oncogenes - Staging/grading - Carcinogenesis - Carcinogen - Research - Paraneoplastic syndrome - List of oncology-related terms |
Tumor markers |
|---|
| Alpha-fetoprotein/AFP-L3 - CA-125 - CA 19-9 - CD30 - Autocrine motility factor - Carcinoembryonic antigen - βHCG - erbB-2 receptor - erbB-3 receptor - NANOG - Neprilysin - Normetanephrine - PCNA - Prostate specific antigen - Synaptophysin |
Pharmacotherapy
Chemotherapeutic agents/Antineoplastic agents (L01) | |
|---|---|
| Alkylating and alkylating-like agents | Nitrogen mustards: (Chlorambucil, Chlormethine, Cyclophosphamide, Ifosfamide, Melphalan, Bendamustine, Uramustine)
Nitrosoureas:(Carmustine, Fotemustine, Lomustine, Streptozocin) Platinum (alkylating-like): (Carboplatin, Cisplatin, Oxaliplatin, Triplatin tetranitrate, Satraplatin) Alkyl sulfonates:(Busulfan, Treosulfan) Hydrazines:(Procarbazine, Dacarbazine, Temozolomide) Aziridines:(ThioTEPA) |
| Antimetabolites | Folic acid: (Aminopterin, Methotrexate, Pemetrexed, Raltitrexed).
Purine:(Cladribine, Clofarabine, Fludarabine, Mercaptopurine, Pentostatin, Thioguanine) Pyrimidine:(Capecitabine, Cytarabine, Decitabine, Fluorouracil, Floxuridine, Gemcitabine) |
| Spindle poison/mitotic inhibitor | Taxane: (Docetaxel, Larotaxel, Paclitaxel). Vinca: (Vinblastine, Vincristine, Vindesine, Vinorelbine). |
| Cytotoxic/antitumor antibiotics | Anthracycline family: (Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitoxantrone, Pixantrone, Valrubicin) streptomyces (Actinomycin, Bleomycin, Mitomycin, Plicamycin) - Hydroxyurea |
| Topoisomerase inhibitors | Camptotheca: (Camptothecin, Topotecan, Irinotecan, Rubitecan), Podophyllum:(Etoposide, Teniposide) |
| CI monoclonal antibodies | Receptor tyrosine kinase (Cetuximab, Panitumumab, Trastuzumab) - CD20 (Rituximab, Tositumomab) - other (Alemtuzumab, Bevacizumab, Gemtuzumab) |
| Photosensitizers | Aminolevulinic acid, Methyl aminolevulinate, Porfimer sodium, Verteporfin |
| Tyrosine kinase inhibitors | Axitinib, Bosutinib, Cediranib, Dasatinib, Erlotinib, Gefitinib, Imatinib, Lapatinib, Lestaurtinib, Nilotinib, Semaxanib, Sorafenib, Sunitinib, Vandetanib |
| Cyclin-dependent kinase inhibitor | Seliciclib |
| Other | retinoids (Alitretinoin, Tretinoin), Fusion protein (Aflibercept) - Altretamine, Amsacrine, Anagrelide, Arsenic trioxide, Asparaginase (Pegaspargase), Bexarotene, Bortezomib, Celecoxib, Denileukin diftitox, Elesclomol, Estramustine, Irofulven, Ixabepilone, Masoprocol, Mitotane, Oblimersen, Testolactone, Tipifarnib, Trabectedin |
Detoxifying agents for antineoplastic treatment (V03AF) |
|---|
| Mesna - Dexrazoxane - Calcium folinate - Calcium levofolinate - Amifostine - Sodium folinate - Rasburicase - Palifermin |
| ||||
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
