ART4

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

(Redirected from Dombrock antigen system)
Jump to: navigation, search
ADP-ribosyltransferase 4 (Dombrock blood group)
Identifiers
Symbol(s) ART4; CD297; DO; DOK1
External IDs OMIM: 110600 MGI: 1202710 Homologene: 10883
RNA expression pattern

Image:PBB GE ART4 207220 at tn.png

More reference expression data

Orthologs
Human Mouse
Entrez 420 109978
Ensembl ENSG00000111339 ENSMUSG00000030217
Uniprot Q93070 na
Refseq NM_021071 (mRNA)
NP_066549 (protein) 		NM_026639 (mRNA)
NP_080915 (protein)
Location Chr 12: 14.87 - 14.89 Mb Chr 6: 136.81 - 136.82 Mb
Pubmed search [1] [2]

WikiDoc Resources for

ART4

Articles

Most recent articles on ART4

Most cited articles on ART4

Review articles on ART4

Articles on ART4 in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on ART4

Images of ART4

Photos of ART4

Podcasts & MP3s on ART4

Videos on ART4

Evidence Based Medicine

Cochrane Collaboration on ART4

Bandolier on ART4

TRIP on ART4

Clinical Trials

Ongoing Trials on ART4 at Clinical Trials.gov

Trial results on ART4

Clinical Trials on ART4 at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on ART4

NICE Guidance on ART4

NHS PRODIGY Guidance

FDA on ART4

CDC on ART4

Books

Books on ART4

News

ART4 in the news

Be alerted to news on ART4

News trends on ART4

Commentary

Blogs on ART4

Definitions

Definitions of ART4

Patient Resources / Community

Patient resources on ART4

Discussion groups on ART4

Patient Handouts on ART4

Directions to Hospitals Treating ART4

Risk calculators and risk factors for ART4

Healthcare Provider Resources

Symptoms of ART4

Causes & Risk Factors for ART4

Diagnostic studies for ART4

Treatment of ART4

Continuing Medical Education (CME)

CME Programs on ART4

International

ART4 en Espanol

ART4 en Francais

Businness

ART4 in the Marketplace

Patents on ART4

Experimental / Informatics

List of terms related to ART4

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3] Phone:617-525-6884

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [4] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

ADP-ribosyltransferase 4 (Dombrock blood group), also known as ART4, is a human gene.[1] ART4 has also been designated as CD297 (cluster of differentiation 297).


This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known.[1]

References

Further reading

  • Reid ME (2003). "The Dombrock blood group system: a review.". Transfusion 43 (1): 107-14. PMID 12519438.
  • Tippett P (1967). "Genetics of the Dombrock blood group system.". J. Med. Genet. 4 (1): 7-11. PMID 6034522.
  • Eiberg H, Mohr J (1996). "Dombrock blood group (DO): assignment to chromosome 12p.". Hum. Genet. 98 (5): 518-21. PMID 8882867.
  • Koch-Nolte F, Haag F, Braren R, et al. (1997). "Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins.". Genomics 39 (3): 370-6. doi:10.1006/geno.1996.4520. PMID 9119374.
  • Mauthe J, Coghlan G, Zelinski T (2000). "Confirmation of the assignment of the Dombrock blood group locus (DO) to chromosome 12p: narrowing the boundaries to 12p12.3-p13.2.". Vox Sang. 79 (1): 53-6. PMID 10971215.
  • Gubin AN, Njoroge JM, Wojda U, et al. (2000). "Identification of the dombrock blood group glycoprotein as a polymorphic member of the ADP-ribosyltransferase gene family.". Blood 96 (7): 2621-7. PMID 11001920.
  • Wu GG, Jin SZ, Deng ZH, Zhao TM (2002). "Polymerase chain reaction with sequence-specific primers-based genotyping of the human Dombrock blood group DO1 and DO2 alleles and the DO gene frequencies in Chinese blood donors.". Vox Sang. 81 (1): 49-51. PMID 11520417.
  • Rios M, Hue-Roye K, Øyen R, et al. (2002). "Insights into the Holley- and Joseph- phenotypes.". Transfusion 42 (1): 52-8. PMID 11896313.
  • Rios M, Storry JR, Hue-Roye K, et al. (2002). "Two new molecular bases for the Dombrock null phenotype.". Br. J. Haematol. 117 (3): 765-7. PMID 12028057.
  • Glowacki G, Braren R, Firner K, et al. (2003). "The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.". Protein Sci. 11 (7): 1657-70. PMID 12070318.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
  • Grahnert A, Friedrich M, Engeland K, Hauschildt S (2005). "Analysis of mono-ADP-ribosyltransferase 4 gene expression in human monocytes: splicing pattern and potential regulatory elements.". Biochim. Biophys. Acta 1730 (3): 173-86. doi:10.1016/j.bbaexp.2005.08.001. PMID 16140404.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

v • d • e
Proteins: clusters of differentiation (see also list of human clusters of differentiation)
1-50CD1 (CD1a-c, CD1d) - CD2 - CD3 - CD4 - CD5 - CD8 - CD9 - CD10 - CD11 (CD11a, CD11b, CD11c) - CD13 - CD14 - CD15 - CD16 - CD18 - CD19 - CD20 - CD21 - CD22 - CD23 - CD24 - CD25 - CD26 - CD27 - CD28 - CD29 - CD30 - CD31 - CD32 - CD33 - CD34 - CD35 - CD36 - CD37 -CD38 - CD40 - CD43 - CD44 - CD45 - CD46 - CD49 (CD49a, CD49b, CD49c, CD49d)
51-100CD52 - CD53 - CD54 - CD55 - CD56 - CD58 - CD59 - CD61 - CD62 (CD62E, CD62L, CD62P) - CD63 - CD64 - CD66e - CD68 - CD70 - CD71 - CD72 - CD79 - CD80 - CD81 - CD82 - CD83 - CD86 - CD88 - CD89 - CD90 - CD94 - CD95 - CD97 - CD98
101-350CD103 - CD106 - CD114 - CD116 - CD117 - CD118 - CD120 - CD122 - CD130 - CD131 - CD132 - CD133 - CD134 - CD135 - CD137 - CD138 - CD141 - CD142 - CD143 - CD146 - CD147 - CD151 - CD152 - CD153 - CD154 - CD155 - CD162 - CD164 - CD169 - CD184 - CD206 - CD209 - CD257 - CD278 - CD281 - CD282 - CD283 - CD304
v • d • e
WikiDoc Research Resources for ART4
Articles on ART4Most recent articles on ART4 • Most cited articles on ART4 • Review articles on ART4 • Articles on ART4 in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on ART4Powerpoint slides on ART4 • Images of ART4 • Photos of ART4 • Podcasts & MP3s on ART4 • Videos on ART4
Evidence Based Medicine Regarding ART4Cochrane Collaboration on ART4 • Bandolier on ART4 • TRIP on ART4
Cost Effectiveness of ART4Cost Effectiveness of ART4
Clinical Trials Involving ART4Ongoing Trials on ART4 at Clinical Trials.gov • Trial results on ART4 • Clinical Trials on ART4 at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding ART4US National Guidelines Clearinghouse on ART4 • NICE Guidance on ART4 • NHS PRODIGY Guidance • FDA on ART4 • CDC on ART4
Textbook Information on ART4Books and Textbook Information on ART4
Pharmacology Resources on ART4Dosing of ART4 • Drug interactions with ART4 • Side effects of ART4 • Allergic reactions to ART4 • Overdose information on ART4 • Carcinogenicity information on ART4 • ART4 in pregnancy • Pharmacokinetics of ART4 •
Genetics, Pharmacogenomics, and Proteinomics of ART4Genetics of ART4 • Pharmacogenomics of ART4 • Proteomics of ART4
Newstories on ART4ART4 in the news • Be alerted to news on ART4 • News trends on ART4
Commentary on ART4Blogs on ART4
Patient Resources on ART4Patient resources on ART4 • Discussion groups on ART4 • Patient Handouts on ART4 • Directions to Hospitals Treating ART4 • Risk calculators and risk factors for ART4
Healthcare Provider Resources on ART4Symptoms of ART4 • Causes & Risk Factors for ART4 • Diagnostic studies for ART4 • Treatment of ART4
Continuing Medical Education (CME) Programs on ART4CME Programs on ART4
International Resources on ART4ART4 en Espanol • ART4 en Francais
Business Resources on ART4ART4 in the Marketplace • Patents on ART4
Informatics Resources on ART4List of terms related to ART4


WikiDoc Help Menu

Quick Start..

Editing basics

Advanced editing

Communicating your edits

Help Videos You Can Watch


Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

Retrieved from "http://www.wikidoc.org/index.php/ART4"
Personal tools