N-arachidonoyl-dopamine

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N-arachidonoyl-dopamine, or NADA is a ligand (or chemical 'key') agonist (activator) to CB1 receptors which is an activation site for endocannabinoid and endovanilloid (aka vanilloid) ligands[1]. Specifically, NADA binds to both TRPV1 (a TRP-vanilloid cation channel receptor) and CB1 (an endocannabinoid receptor), a peculiarity among neurochemicals which normally bind to only one type of receptor.

References

  1. ↑ Ralevic V. (2003). "Cannabinoid modulation of peripheral autonomic and sensory neurotransmission". European journal of pharmacology. 472 (1–2): 1–21. PMID 12860468. Unknown parameter |month= ignored (help)









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