MK-9470

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Template:Chembox E number
MK-9470
IUPAC name N-((2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl)-2-methyl-2-(5-methylpyridin-2-yloxy)propanamide
Identifiers
3D model (JSmol)
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Properties
C29H33N3O3
Molar mass 471.59 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

MK-9470 is a synthetic compound, which binds to the cannabinoid receptor and functions as an inverse agonist.[1]

References

  1. Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ (2007). "[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor". Proc. Natl. Acad. Sci. U.S.A. 104 (23): 9800–5. doi:10.1073/pnas.0703472104. PMID 17535893.




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