JWH-147

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JWH-147
File:JWH-147.svg
Legal status
Legal status
  • In general: legal
Identifiers
E number{{#property:P628}}
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Chemical and physical data
FormulaC27H27NO
Molar mass381.51 g/mol
3D model (JSmol)

JWH-147 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 11.0nM at CB1 vs 7.1nM at CB2.[1]


References

  1. Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters 2006; 16:5432-5435.



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