AM-906

AM-906

File:AM-906.png
Gene therapy
Clinical data
Physiological data
Legal status
Pharmacokinetic data
Identifiers
IUPAC name (6aR,9R,10aR)-3-[(Z)-hept-1-enyl]-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
PubChem Template:Abbreviation	10089808
Chemical and physical data
Formula	C23H34O3
Molar mass	358.513 g/mol
3D model (JSmol)	Interactive image
SMILES CCCCCC=Cc(cc1O)cc(OC(C)(C)C2CC3)c1C2CC3CO

AM-906 is an analgesic drug which is a cannabinoid agonist with a conformationally restricted side chain. It is a potent and selective agonist for the CB₁ cannabinoid receptor, with a Ki of 0.8nM at CB₁ vs 9.5nM at CB₂, a selectivity of almost 12x.