A-41988

A-41988
	File:A-41988.png
Identifiers
	IUPAC name 8-[5-(4-fluorophenyl)pentan-2-yl]-5,5-dimethyl-2-prop-2-ynyl-3,4-dihydro-1H-chromeno[4,3-c]pyridin-10-ol;
CAS Number	52763-30-1;
PubChem CID	3085018;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C28H32FNO2
Molar mass	433.556 g/mol
3D model (JSmol)	Interactive image;
	SMILES c4cc(F)ccc4CCCC(C)c3cc(O)c1C=2CN(CC#C)CCC=2C(C)(C)Oc1c3;

A-41988 (BW29Y) is an analgesic drug which acts as a cannabinoid agonist. It was developed by Abbott Laboratories in the 1970s,^[1]^[2] and researched for potential use in the treatment of glaucoma,^[3] but never commercialised.

References

↑ Winn M, Arendsen D, Dodge P, Dren A, Dunnigan D, Hallas R, Hwang K, Kyncl J, Lee YH, Plotnikoff N, Young P, Zaugg H. Drugs derived from cannabinoids. 5Δ,6a,10a,-Tetrahydrocannabinol and heterocyclic analogs containing aromatic side chains. Journal of Medicinal Chemistry 1976; 19(4):461-471. PMID 817021
↑ Guterman A, Somani P, Bachand RT. Clinical Pharmacology and Therapeutics 1979; 25:227.
↑ Tiedeman JS, Shields MB, Weber PA, Crow JW, Cocchetto DM, Harris WA, Howes JF. Effect of synthetic cannabinoids on elevated intraocular pressure. Ophthalmology. 1981 Mar;88(3):270-7. PMID 7015221

Identifiers
File:A-41988.png
IUPAC name 8-[5-(4-fluorophenyl)pentan-2-yl]-5,5-dimethyl-2-prop-2-ynyl-3,4-dihydro-1H-chromeno[4,3-c]pyridin-10-ol
CAS Number	52763-30-1
PubChem CID	3085018
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₈H₃₂FNO₂
Molar mass	433.556 g/mol
3D model (JSmol)	Interactive image
SMILES c4cc(F)ccc4CCCC(C)c3cc(O)c1C=2CN(CC#C)CCC=2C(C)(C)Oc1c3