Leukotriene B4 receptor 2

Leukotriene B4 receptor 2
Identifiers
Symbols	LTB4R2 ; BLT2; BLTR2; JULF2; KPG_004; NOP9
External IDs	Template:OMIM5 Template:MGI HomoloGene: 10519
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Leukotriene B4 receptor 2, also known as LTB4R2, is a human gene.

This is a low-affinity receptor for leukotrienes, especially leukotriene B4. It mediates chemotaxis of granulocytes and macrophages.

See also

• Eicosanoid receptor

Further reading

• Tager AM, Luster AD (2004). "BLT1 and BLT2: the leukotriene B(4) receptors". Prostaglandins Leukot. Essent. Fatty Acids. 69 (2–3): 123–34. PMID 12895595.
• Kamohara M, Takasaki J, Matsumoto M; et al. (2000). "Molecular cloning and characterization of another leukotriene B4 receptor". J. Biol. Chem. 275 (35): 27000–4. doi:10.1074/jbc.C000382200. PMID 10889186.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tryselius Y, Nilsson NE, Kotarsky K; et al. (2000). "Cloning and characterization of cDNA encoding a novel human leukotriene B(4) receptor". Biochem. Biophys. Res. Commun. 274 (2): 377–82. doi:10.1006/bbrc.2000.3152. PMID 10913346.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nilsson NE, Tryselius Y, Owman C (2000). "Genomic organization of the leukotriene B(4) receptor locus of human chromosome 14". Biochem. Biophys. Res. Commun. 274 (2): 383–8. doi:10.1006/bbrc.2000.3153. PMID 10913347.CS1 maint: Multiple names: authors list (link)
• Kato K, Yokomizo T, Izumi T, Shimizu T (2000). "Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene". J. Exp. Med. 192 (3): 413–20. PMID 10934229.CS1 maint: Multiple names: authors list (link)
• Yokomizo T, Kato K, Terawaki K; et al. (2000). "A second leukotriene B(4) receptor, BLT2. A new therapeutic target in inflammation and immunological disorders". J. Exp. Med. 192 (3): 421–32. PMID 10934230.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang S, Gustafson E, Pang L; et al. (2001). "A novel hepatointestinal leukotriene B4 receptor. Cloning and functional characterization". J. Biol. Chem. 275 (52): 40686–94. doi:10.1074/jbc.M004512200. PMID 11006272.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takeda S, Kadowaki S, Haga T; et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. PMID 12044878.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hashimoto A, Endo H, Hayashi I; et al. (2003). "Differential expression of leukotriene B4 receptor subtypes (BLT1 and BLT2) in human synovial tissues and synovial fluid leukocytes of patients with rheumatoid arthritis". J. Rheumatol. 30 (8): 1712–8. PMID 12913925.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yoo MH, Song H, Woo CH; et al. (2005). "Role of the BLT2, a leukotriene B4 receptor, in Ras transformation". Oncogene. 23 (57): 9259–68. doi:10.1038/sj.onc.1208151. PMID 15489890.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Qiu H, Johansson AS, Sjöström M; et al. (2006). "Differential induction of BLT receptor expression on human endothelial cells by lipopolysaccharide, cytokines, and leukotriene B4". Proc. Natl. Acad. Sci. U.S.A. 103 (18): 6913–8. doi:10.1073/pnas.0602208103. PMID 16624877.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lundeen KA, Sun B, Karlsson L, Fourie AM (2006). "Leukotriene B4 receptors BLT1 and BLT2: expression and function in human and murine mast cells". J. Immunol. 177 (5): 3439–47. PMID 16920986.CS1 maint: Multiple names: authors list (link)

External links

• IUPHAR GPCR Database - Leukotriene receptors
  
• LTB4R2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• Receptors,+Leukotriene+B4 at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.