Mepyramine
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| Image:Mepyramine.png | |
| Mepyramine
| |
| Systematic (IUPAC) name | |
| N1-(4-methoxybenzyl)- N2,N2-dimethyl- N1-(pyridin-2-yl)ethane- 1,2-diamine | |
| Identifiers | |
| CAS number | |
| ATC code | R06 D04AA02 |
| PubChem | ? |
| Chemical data | |
| Formula | C17H23N3O |
| Mol. mass | 285.38 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Mepyramine (INN, also known as pyrilamine) [1] is a first generation antihistamine, targeting the H1 receptor. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
It is used in over-the-counter combination products for colds and menstrual symptoms.[2]
Side effects may include sedation/drowsiness, muscle weakness, and insomnia.[3]
References
- ↑ Parsons, M. E. and Ganellin, C. R. (2006). "Histamine and its receptors". British Journal of Pharmacology 147: S127–S135. PMID 16402096.
- ↑ http://www.uspharmacist.com/oldformat.asp?url=newlook/files/Cons/sep00cyp.cfm
- ↑ http://www.drugs.com/pdr/pyrilamine_maleate.html
External links
Antipruritics (D04) | |
|---|---|
| Antihistamines for topical use | Thonzylamine - Mepyramine - Thenalidine - Tripelennamine - Chloropyramine - Promethazine - Tolpropamine - Dimetindene - Clemastine - Bamipine - Isothipendyl - Diphenhydramine - Chlorphenoxamine |
| Anesthetics for topical use | Lidocaine - Cinchocaine - Oxybuprocaine - Benzocaine - Quinisocaine - Tetracaine - Pramocaine |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
