Acrivastine

Acrivastine
Systematic (IUPAC) name
(E)-3-{6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl- prop-1-enyl]pyridin-2-yl}prop-2-enoic acid
Identifiers
CAS number	87848-99-5
ATC code	R06AX18
PubChem	5284514
Chemical data
Formula	C22H24N2O2
Mol. mass	348.438 g/mol
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	1.5 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

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Overview

Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors.

It is sold under the brand name Benadryl Allergy Relief in the U.K. by Pfizer, not to be confused with Benadryl Once a Day, which is cetirizine and is also sold by Pfizer in the U.K. This drug is currently not available as a generic in the U.K.

In the U.S., acrivastine is the active ingrediant in the Semprex brand. Semprex-D is also acrivastine based, but also contains a decongestant.

References

da:Acrivastin