Eticyclidine
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| Image:PCE.png | |
| Eticyclidine
| |
| Systematic (IUPAC) name | |
| N-ethyl-1-phenylcyclohexylamine | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C14H21N |
| Mol. mass | 203.323 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
Schedule I / Class A |
| Routes | ? |
Eticyclidine (PCE) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400, but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[1] PCE is slightly more potent than PCP and has similar effects, but its unpleasant taste and tendency to cause nausea made it less accepted by users.[2] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.
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See also
References
- ↑ Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477
- ↑ http://www.erowid.org/archive/rhodium/chemistry/pcp/sar.html
Dissociative hallucinogens | |
|---|---|
| Kappa agonists | Cyclazocine - Enadoline - Salvinorin A - Pentazocine - Tifluadom |
| NMDA receptor antagonists | 2-MDP - Dexoxadrol - Dextromethorphan - Dizocilpine - Esketamine - Etoxadrol - Ketamine - PCE - PCP - PCPy - TCP - Tiletamine |
| Others | Efavirenz - Muscimol - Nitrous oxide - Xenon |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
