Dopamine agonist
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Overview
A dopamine agonist is a compound that activates dopamine receptors, mimicking the effect of the neurotransmitter dopamine.
Uses
Some medical drugs act as dopamine agonists; they are typically used for treating Parkinson's disease, and may be useful for restless legs syndrome (RLS). Both Requip (Ropinirole) and Mirapex (Pramipexole) are FDA approved for the treatment of RLS.
There is also an ongoing clinical trial to test the effectiveness of Requip (Ropinirole), a dopamine agonist, in reversing the symptoms of SSRI induced sexual dysfunction. [1]
Examples
Examples of dopamine agonists include:
- Parlodel (bromocriptine)
- Permax (Pergolide) - Removed from market March 29,2007.[2]
- Mirapex (Pramipexole)
- Requip (Ropinirole)
- Apokyn (apomorphine)
See also
References
- ↑ ClinicalTrials.gov NCT00334048 - "Treating Sexual Dysfunction From SSRI Medication: a Study Comparing Requip CR to Placebo"
- ↑ http://www.fda.gov/bbs/topics/NEWS/2007/NEW01596.html
External links
Anti-parkinson drugs: dopaminergic agents (N04B) | |
|---|---|
| Dopa and derivatives | Levodopa, Melevodopa, Etilevodopa |
| Adamantane derivatives | Amantadine |
| Dopamine agonists | Apomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958 |
| MAOIs | Selegiline, Rasagiline |
| Other | Tolcapone, Entacapone, Budipine |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
