Tachykinin receptor 3

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Tachykinin receptor 3
Identifiers
Symbols TACR3 ; MGC148060; MGC148061; NK3R; TAC3RL
External IDs Template:OMIM5 Template:MGI HomoloGene824
RNA expression pattern
File:PBB GE TACR3 208183 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Tachykinin receptor 3, also known as TACR3, is a human gene.[1]

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B.[1]

See also

References

  1. 1.0 1.1 "Entrez Gene: TACR3 tachykinin receptor 3".

Further reading

  • Khawaja AM, Rogers DF (1996). "Tachykinins: receptor to effector". Int. J. Biochem. Cell Biol. 28 (7): 721–38. PMID 8925404.
  • Advenier C, Lagente V, Boichot E (1997). "The role of tachykinin receptor antagonists in the prevention of bronchial hyperresponsiveness, airway inflammation and cough". Eur. Respir. J. 10 (8): 1892–906. PMID 9272936.
  • Buell G, Schulz MF, Arkinstall SJ; et al. (1992). "Molecular characterisation, expression and localisation of human neurokinin-3 receptor". FEBS Lett. 299 (1): 90–5. PMID 1312036.
  • Takahashi K, Tanaka A, Hara M, Nakanishi S (1992). "The primary structure and gene organization of human substance P and neuromedin K receptors". Eur. J. Biochem. 204 (3): 1025–33. PMID 1312928.
  • Xie GX, Miyajima A, Goldstein A (1992). "Expression cloning of cDNA encoding a seven-helix receptor from human placenta with affinity for opioid ligands". Proc. Natl. Acad. Sci. U.S.A. 89 (9): 4124–8. PMID 1315051.
  • Huang RR, Cheung AH, Mazina KE; et al. (1992). "cDNA sequence and heterologous expression of the human neurokinin-3 receptor". Biochem. Biophys. Res. Commun. 184 (2): 966–72. PMID 1374246.
  • Dion S, Corcos J, Carmel M; et al. (1988). "Substance P and neurokinins as stimulants of the human isolated urinary bladder". Neuropeptides. 11 (2): 83–7. PMID 2452993.
  • Krause JE, Staveteig PT, Mentzer JN; et al. (1997). "Functional expression of a novel human neurokinin-3 receptor homolog that binds [3H]senktide and [125I-MePhe7]neurokinin B, and is responsive to tachykinin peptide agonists". Proc. Natl. Acad. Sci. U.S.A. 94 (1): 310–5. PMID 8990205.
  • Brunelleschi S, Bordin G, Colangelo D, Viano I (1999). "Tachykinin receptors on human monocytes: their involvement in rheumatoid arthritis". Neuropeptides. 32 (3): 215–23. PMID 10189055.
  • Page NM, Woods RJ, Gardiner SM; et al. (2000). "Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia". Nature. 405 (6788): 797–800. doi:10.1038/35015579. PMID 10866201.
  • Bellucci F, Carini F, Catalani C; et al. (2002). "Pharmacological profile of the novel mammalian tachykinin, hemokinin 1". Br. J. Pharmacol. 135 (1): 266–74. doi:10.1038/sj.bjp.0704443. PMID 11786503.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Graham GJ, Stevens JM, Page NM; et al. (2005). "Tachykinins regulate the function of platelets". Blood. 104 (4): 1058–65. doi:10.1182/blood-2003-11-3979. PMID 15130944.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Page NM, Dakour J, Morrish DW (2006). "Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsia". Mol. Hum. Reprod. 12 (7): 427–33. doi:10.1093/molehr/gal025. PMID 16709596.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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