TAS1R3

Taste receptor, type 1, member 3
Identifiers
Symbols	TAS1R3 ; T1R3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 12890
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Taste receptor, type 1, member 3, also known as TAS1R3, is a human gene.

The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners.[supplied by OMIM]

See also

• Taste receptor

Further reading

• Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS (2007). "The receptors and cells for mammalian taste". Nature. 444 (7117): 288–94. doi:10.1038/nature05401. PMID 17108952.CS1 maint: Multiple names: authors list (link)
• Montmayeur JP, Liberles SD, Matsunami H, Buck LB (2001). "A candidate taste receptor gene near a sweet taste locus". Nat. Neurosci. 4 (5): 492–8. doi:10.1038/87440. PMID 11319557.CS1 maint: Multiple names: authors list (link)
• Max M, Shanker YG, Huang L; et al. (2001). "Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac". Nat. Genet. 28 (1): 58–63. doi:10.1038/88270. PMID 11326277.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nelson G, Chandrashekar J, Hoon MA; et al. (2002). "An amino-acid taste receptor". Nature. 416 (6877): 199–202. doi:10.1038/nature726. PMID 11894099.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Li X, Staszewski L, Xu H; et al. (2002). "Human receptors for sweet and umami taste". Proc. Natl. Acad. Sci. U.S.A. 99 (7): 4692–6. doi:10.1073/pnas.072090199. PMID 11917125.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Spadaccini R, Trabucco F, Saviano G; et al. (2003). "The mechanism of interaction of sweet proteins with the T1R2-T1R3 receptor: evidence from the solution structure of G16A-MNEI". J. Mol. Biol. 328 (3): 683–92. PMID 12706725.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ariyasu T, Matsumoto S, Kyono F; et al. (2004). "Taste receptor T1R3 is an essential molecule for the cellular recognition of the disaccharide trehalose". In Vitro Cell. Dev. Biol. Anim. 39 (1–2): 80–8. doi:10.1290/1543-706X(2003)039<0080:TRTIAE>2.0.CO;2. PMID 12892531.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jiang P, Ji Q, Liu Z; et al. (2004). "The cysteine-rich region of T1R3 determines responses to intensely sweet proteins". J. Biol. Chem. 279 (43): 45068–75. doi:10.1074/jbc.M406779200. PMID 15299024.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xu H, Staszewski L, Tang H; et al. (2005). "Different functional roles of T1R subunits in the heteromeric taste receptors". Proc. Natl. Acad. Sci. U.S.A. 101 (39): 14258–63. doi:10.1073/pnas.0404384101. PMID 15353592.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Taniguchi K (2005). "Expression of the sweet receptor protein, T1R3, in the human liver and pancreas". J. Vet. Med. Sci. 66 (11): 1311–4. PMID 15585941.
• Jiang P, Cui M, Zhao B; et al. (2005). "Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste". J. Biol. Chem. 280 (15): 15238–46. doi:10.1074/jbc.M414287200. PMID 15668251.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Galindo-Cuspinera V, Winnig M, Bufe B; et al. (2006). "A TAS1R receptor-based explanation of sweet 'water-taste'". Nature. 441 (7091): 354–7. doi:10.1038/nature04765. PMID 16633339.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Behrens M, Bartelt J, Reichling C; et al. (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression". J. Biol. Chem. 281 (29): 20650–9. doi:10.1074/jbc.M513637200. PMID 16720576.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Koizumi A, Nakajima K, Asakura T; et al. (2007). "Taste-modifying sweet protein, neoculin, is received at human T1R3 amino terminal domain". Biochem. Biophys. Res. Commun. 358 (2): 585–9. doi:10.1016/j.bbrc.2007.04.171. PMID 17499612.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.