Relaxin/insulin-like family peptide receptor 4

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Relaxin/insulin-like family peptide receptor 4
Identifiers
Symbols RXFP4 ; GPCR142; GPR100; MGC126556; MGC126558; RLN3R2
External IDs Template:OMIM5 Template:MGI HomoloGene18775
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Relaxin/insulin-like family peptide receptor 4, also known as RXFP4, is a human gene.[1]

GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003).[supplied by OMIM][1]

See also

References

  1. 1.0 1.1 "Entrez Gene: RXFP4 relaxin/insulin-like family peptide receptor 4".

Further reading

  • Bathgate RA, Ivell R, Sanborn BM; et al. (2005). "Receptors for relaxin family peptides". Ann. N. Y. Acad. Sci. 1041: 61–76. doi:10.1196/annals.1282.010. PMID 15956688.
  • Bathgate RA, Ivell R, Sanborn BM; et al. (2006). "International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides". Pharmacol. Rev. 58 (1): 7–31. doi:10.1124/pr.58.1.9. PMID 16507880.
  • Takeda S, Kadowaki S, Haga T; et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. PMID 12044878.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Liu C, Chen J, Sutton S; et al. (2004). "Identification of relaxin-3/INSL7 as a ligand for GPCR142". J. Biol. Chem. 278 (50): 50765–70. doi:10.1074/jbc.M308996200. PMID 14522967.
  • Boels K, Schaller HC (2004). "Identification and characterisation of GPR100 as a novel human G-protein-coupled bradykinin receptor". Br. J. Pharmacol. 140 (5): 932–8. doi:10.1038/sj.bjp.0705521. PMID 14530218.
  • Fredriksson R, Höglund PJ, Gloriam DE; et al. (2003). "Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives". FEBS Lett. 554 (3): 381–8. PMID 14623098.
  • Liu C, Chen J, Kuei C; et al. (2005). "Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7". Mol. Pharmacol. 67 (1): 231–40. doi:10.1124/mol.104.006700. PMID 15465925.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Liu C, Kuei C, Sutton S; et al. (2005). "INSL5 is a high affinity specific agonist for GPCR142 (GPR100)". J. Biol. Chem. 280 (1): 292–300. doi:10.1074/jbc.M409916200. PMID 15525639.
  • Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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